Comprehensive HMGB1 ELISA Kits

HMGB1 is a multifunctional protein with various roles in different cellular compartments. Extracellular HMGB1 is a representative marker of damage‐associated molecular patterns (DAMPs) which trigger innate and adaptive immune responses. Excessive serum HMGB1 level is associated with pathologies of inflammatory diseases including sepsis, arteriosclerosis, rheumatoid arthritis, and neuroinflammatory diseases. Besides, high level of tumor-derived HMGB1 is associated with poorer prognosis in patients. However, elevated HMGB1 level is a reliable marker to detect chemo-/radiotherapy-induced necrotic death in tumor cells. HMGB1 released from necrotic tumor cells triggers immunogenic cell death (ICD) to kill neighboring cancer cells.

Extracellular HMGB1 is a useful marker to evaluate necrosis, severity of inflammatory diseases, cancer prognosis, therapeutic effects of chemo-/radiotherapy, and ICD. arigo offers comprehensive HMGB1 ELISA kits to facilitate the quantification of HMGB1.

 

 

Comprehensive HMGB1 ELISA kits

Human HMGB1 ELISA Kit (ARG81185) Mouse/Rat HMGB1 ELISA Kit (ARG81310) Serum HMGB1 ELISA Kit (ARG81351) Benefits ● HMGB1-specific. No cross reactivity with HMGB2. ● Excellent for detecting ICD and necrosis at ng/ml ranges ● Good for plasma, serum, cell culture supernatant, and lysate. ● Multiple citations

 

 

Learn more about HMGB1 quantification

● Detecting the DAMPs in cancer therapy by HMGB1 ELISA kit ● Detecting exosomal HMGB1 for ICD research ● HMGB1, a biomarker and therapeutic target in COVID-19 ● Total solutions for HMGB1 research

 

 

Latest citations of HMGB1 ELISA kits

Mouse/Rat HMGB1 ELISA Kit (ARG81310)	This kit is frequently used for measuring ICD in mice. Zhang et al., (2024) Nat Commun. 15(1):1118. (ICD, data on left) Molina-López et al., (2024) Nat Commun. 15(1):1096. Xu et al., (2024) Cell Rep. 43(8):114591. Furukawa et al., (2024) Cell Death Discov. 10(1):161. (ICD) Fujimoto et al., (2024) Cancer Sci. 115(10):3231-3247. (ICD) Han et al., (2023) Oncoimmunology. 12(1):2238499. (ICD) Tojo et al., (2023) iScience. 26(1):105748. (DAMP) Hu et al., (2023) Life Sci. 322:121653. Nikolos et al., (2022) Nat Commun. 13(1):1487. (DAMP) Kuai et al. (2022) Acta Pharm Sin B. 12(2):967-981. (ICD) Saleh et al. (2022) Part Fibre Toxicol. 19(1):30.
Human HMGB1 ELISA Kit (ARG81185)	This kit is frequently used for studying inflammatory diseases. Huang et al., (2024) Int Immunopharmacol. 127:111397. Yasuda et al., (2023) J Autoimmun. 142:103149. (data on left) Hurtado-Navarro et al., (2023) Cell Rep Med. 4(12):101329. Jung et al., (2023) Biomaterials. 298:122127. (ICD) Yan et al., (2023) Front Immunol. 14:1098140. Yamaki et al., (2023) Cancer Immunol Immunother. 72(8):2799-2812. (ICD) Yang et al., (2023) Int Immunopharmacol. 123:110706. Jung et al., (2022) Biomaterials. 287:121681. (ICD) Li et al., (2022) J Exp Clin Cancer Res. 41(1):74.
Serum HMGB1 ELISA Kit (ARG81351)	This kit is good for both human and rodent. Liu et al., (2024) Adv Sci (Weinh). 11(3):e2305217. (ICD) Luo et al., (2023) ACS Nano. 17(10):8966-8979. (ICD) Yuan et al., (2023) Bioeng Transl Med. 8(6):e10576. (ICD, data on left) Takimoto et al., (2023) iScience. 26(3):106220. Huang et al. (2022) Nanotoday. 44:101500. (ICD) Luo et al., (2022) J Nanobiotechnology. 20(1):228. (ICD)