Pathogenic NLRP3 mutants form constitutively active inflammasomes resulting in immune-metabolic limitation of IL-1β production

ELISA / Mouse / Cell culture supernatant

Cristina Molina-López et al.
Nat Commun.,  (2024)

Redox-responsive polymer micelles co-encapsulating immune checkpoint inhibitors and chemotherapeutic agents for glioblastoma therapy

ELISA / Mouse / Cell culture supernatant

Zhiqi Zhang et al.
Nat Commun.,  (2024)

Nuclear HMGB1 is critical for CD8 T cell IFN-γ production and anti-tumor immunity

ELISA / Mouse Serum / Cell culture supernatant

Zhiguang Xu et al.
Cell Rep.,  (2024)

Overcoming immunotherapy resistance and inducing abscopal effects with boron neutron immunotherapy (B-NIT)

ELISA / Mouse / Serum

Takuya Fujimoto et al.
Cancer Sci.,  (2024)

N-acetylserotonin alleviates retinal ischemia-reperfusion injury via HMGB1/RAGE/NF-κB pathway in rats

ELISA / Rat / Serum

Yu-Ze Zhao et al.
Int J Ophthalmol.,  (2024)

Continuous infiltration of small peritoneal macrophages in the mouse peritoneum through CCR2-dependent and -independent routes during fibrosis and mesothelioma development induced by a multiwalled carbon nanotube, MWNT-7

ELISA / Mouse / Cell culture supernatant

Motomu Shimizu et al.
J. Toxicol. Sci.,  (2023)

Auto- and paracrine rewiring of NIX-mediated mitophagy by insulin-like growth factor-binding protein 7 in septic AKI escalates inflammation-coupling tubular damage

ELSIA / Mouse / Tissue lysate

Bang-Chuan Hu et al.
Life Sci.,  (2023)

Early alveolar epithelial cell necrosis is a potential driver of COVID-19-induced acute respiratory distress syndrome

ELISA / Mouse / Cell culture supernatant

Kentaro Tojo et al.
iScience.,  (2023)

Chemokine-derived oncolytic peptide induces immunogenic cancer cell death and significantly suppresses tumor growth

ELISA / Mouse / Cell culture supernatant

Natsuki Furukawa et al.
Res Sq.,  (2023)

A mechanism of IL-34-induced resistance against cytotoxic anti-cancer therapies such as radiation by X-ray and chemotherapy by Oxaliplatin

ELISA / Mouse / Cell lysate

Nanumi Han et al.
Oncoimmunology.,  (2023)

Hydrogen alleviated cognitive impairment and blood‒brain barrier damage in sepsis-associated encephalopathy by regulating ABC efflux transporters in a PPARα-dependent manner

ELISA / Mouse / Tissue lysate

Yuanyuan Bai et al.
BMC Neurosci.,  (2023)

Perfluorooctyl bromide nanoemulsions holding MnO2 nanoparticles with dual-modality imaging and glutathione depletion enhanced HIFU-eliciting tumor immunogenic cell death

ELISA / Mouse / Cell culture supernatant

XinpingKuai et al.
Acta Pharmaceutica Sinica B,  (2022)

High Dose Local Photon Irradiation Is Crucial in Anti-CTLA-4 Antibody Therapy to Enhance the Abscopal Response in a Murine Pancreatic Carcinoma Model

ELISA / Mouse / Cell culture supernatant

Junya Yamamoto et al.
Cancers (Basel).,  (2022)

Assessment of the toxicity and carcinogenicity of double-walled carbon nanotubes in the rat lung after intratracheal instillation: a two-year study

ELISA / Rat / Pleural lavage fuid

Dina Mourad Saleh et al.
Part Fibre Toxicol,  (2022)

Regulatory mechanisms of HMGB1 and its receptors in polycystic ovary syndrome-driven gravid uterine inflammation

ELISA / Rat / Serum

Min Hu et al.
FEBS J,  (2022)

Cutaneous ischemia-reperfusion injury is exacerbated by IL-36 receptor antagonist deficiency

ELISA / Mouse / Serum

Y Tanaka et al.
J Eur Acad Dermatol Venereol.,  (2022)

Distinct roles of HMGB1 in the regulation of P glycoprotein expression in the liver and kidney of mice with lipopolysaccharide-induced inflammation

ELISA / Mouse / Plasma, Tissue lysate

Atsushi Kawase et al.
Research Square,  (2022)

Cell death-induced immunogenicity enhances chemoimmunotherapeutic response by converting immune-excluded into T-cell inflamed bladder tumors

ELISA / Mouse / Serum, Cell culture supernatant

Fotis Nikolos et al.
Nat Commun.,  (2022)

Distinct roles of HMGB1 in the regulation of P‑glycoprotein expression in the liver and kidney of mice with lipopolysaccharide‑induced inflammation

ELISA / Mouse / Plasma, Tissue lysate

Atsushi Kawase et al.
Mol Med Rep,  (2022)

Enhanced Therapeutic Efficacy of Combining Losartan and Chemo-Immunotherapy for Triple Negative Breast Cancer

ELISA / Mouse / Culture supernatant

Qing Zhao et al.
Front Immunol.,  (2022)

Radiation therapy enhances systemic antitumor efficacy in PD-L1 therapy regardless of sequence of radiation in murine osteosarcoma

ELISA / Mouse / Cell culture supernatant

Shohei Katsuki  et al.
PLoS One.,  (2022)

Sodium Butyrate Alleviates Intestinal Inflammation in Mice with Necrotizing Enterocolitis

ELISA / Mouse / Tissue lysate

Qian Sun et al.
Mediators Inflamm.,  (2021)

Oxygen-Delivering Polyfluorocarbon Nanovehicles Improve Tumor Oxygenation and Potentiate Photodynamic-Mediated Antitumor Immunity.

ELISA / Mouse

Zhiwan Wang et al.
ACS Nano.,  (2021)

Glycyrrhizin ameliorates melanoma cell extravasation into mouse lungs by regulating signal transduction through HMGB1 and its receptors

ELISA / Mouse / Plasma

Keiichi Hiramoto et al.
J Clin Biochem Nutr.,  (2021)

Homologous-targeted and tumor microenvironment-activated hydroxyl radical nanogenerator for enhanced chemoimmunotherapy of non-small cell lung cancer

ELISA / Mouse / Cell culture supernatant

LingxiaLiang et al.
Chemical Engineering Journal,  (2021)

Combination of Cisplatin and Irradiation Induces Immunogenic Cell Death and Potentiates Postirradiation Anti-PD-1 Treatment Efficacy in Urothelial Carcinoma.

ELISA / Mouse / Cell culture supernatant

Hiroshi Fukushima et al.
Int J Mol Sci.,  (2021)

The Efficacy of Phage Therapy in a Murine Model of Pseudomonas aeruginosa Pneumonia and Sepsis

ELISA / Mouse / Tissue lysate, Serum

Xu Yang et al.
Front Microbiol.,  (2021)

High-density lipoprotein modulates tumor-associated macrophage for chemoimmunotherapy of hepatocellular carcinoma.

ELISA / Mouse / Cell culture supernatant

Junyang Wang et al.
Nano Today.,  (2021)

Clara cell 16 KDa protein mitigates house dust mite-induced airway inflammation and damage via regulating airway epithelial cell apoptosis in a manner dependent on HMGB1-mediated signaling inhibition.

ELISA / Mouse / Serum

Meixuan Liu et al.
Mol Med.,  (2021)

Spatiotemporal depletion of tumor-associated immune checkpoint PD-L1 with near-infrared photoimmunotherapy promotes antitumor immunity

ELISA / Mouse / Cell culture supernatant

Shunichi Taki et al.
J Immunother Cancer.,  (2021)

Comparison of Exosomes Derived from Non- and Gamma-Irradiated Melanoma Cancer Cells as a Potential Antigenic and Immunogenic Source for Dendritic Cell-Based Immunotherapeutic Vaccine.

ELISA / Mouse

Woo Sik Kim et al.
Vaccines (Basel).,  (2020)

Molecular hydrogen alleviates brain injury and cognitive impairment in a chronic sequelae model of murine polymicrobial sepsis.

ELISA / Mouse / Tissue lysate

Yi Jiang et al.
Exp Brain Res.,  (2020)

Tumor-derived HMGB1 induces CD62L dim neutrophil polarization and promotes lung metastasis in triple-negative breast cancer.

ELISA / Mouse / Serum and culture medium

Zhen Wang et al.
Oncogenesis.,  (2020)

Carrier-free nanoassembly of doxorubicin prodrug and siRNA for combinationally inducing immunogenic cell death and reversing immunosuppression.

ELISA / Mouse / Cell culture supernatant

Senbiao Chen et al.
Nano Today.,  (2020)

Syringeable immunotherapeutic nanogel reshapes tumor microenvironment and prevents tumor metastasis and recurrence.

ELISA / Mouse

Song Chanyoung et al.
Nat Commun.,  (2019)

Targeting HMGB1 by ethyl pyruvate ameliorates systemic lupus erythematosus and reverses the senescent phenotype of bone marrow-mesenchymal stem cells.

ELISA / 

Ji Juan et al.
Aging.,  (2019)

Irradiation-induced osteocyte damage promotes HMGB1-mediated osteoclastogenesis in vitro.

ELISA / Mouse

He Feilong et al.
J Cell Physiol.,  (2019)

Carbon ion irradiation enhances the antitumor efficacy of dual immune checkpoint blockade therapy both for local and distant sites in murine osteosarcoma.

ELISA / Mouse

Takahashi Yutaka et al.
Oncotarget.,  (2019)

Inhibition of HMGB1 Promotes Osseointegration under Hyperglycemic Condition through Improvement of BMSC Dysfunction.

ELISA / Rat

Liu Beilei et al.
Oxid Med Cell Longev.,  (2019)