Choose the best HMGB1 neutralizing antibody

Extracellular HMGB1 is a representative marker of damage‐associated molecular patterns (DAMPs) which trigger inflammatory responses. HMGB1 plays a critical role in the pathogenesis of various diseases, such as sepsis, autoimmune disorders, neuroinflammation and cancer. Inhibiting HMGB1 shows a therapeutic potential for attenuating inflammatory diseases and blocking tumor progression.

arigo offers the best HMGB1 neutralizing antibody for basic and clinical research. This monoclonal antibody shows excellent neutralization effect in vitro and in vivo. It has been referenced for studying infectious diseases, cancer, and inflammatory responses.
 

● HMGB1-specific Mouse mAb (Recommended control: ARG20592)
● Effective in vitro & in vivo  neutralization
● Works on human and mouse cells
● Good for ELISA, FACS, Neut, WB
 

Kam et al. for reducing HUVEC migration and tube formation.

You et al. for inhibiting virus-induced BBB permeability.

Vadevoo et al. for inhibiting chemotherapy-induced M2-to-M1 reprogramming.
Tojo et al. for attenuating COVID-19 -induced respiratory syndrome.
Xiao et al. for alleviating stress-induced cell death.
Wang et al. for inhibiting HMGB1-mediated impairment of efferocytosis.