Search Result - Primary Antibodies

  • anti-CD253 / TRAIL antibody [2E5] (PE)
  • Cat. No: ARG54196  (Mouse mAb)
  • Reactivity: Hu
  • Application: FACS
  • Specificity: The clone 2E5 reacts with TRAIL (APO-2L), a 21 kDa cytotoxic protein, activator of rapid apoptosis in tumor cells. TRAIL is mainly expressed in spleen, lung, prostate and also in many other tissues.
  • Conjugation: PE
  • anti-Myc tag antibody [9E10] (biotin)
  • Cat. No: ARG54213  (Mouse mAb)
  • Reactivity: Other
  • Application: FACS
  • Specificity: The antibody 9E10 may be used to detect the cMyc tag.
    The cmyc gene (8q24 on human chromosome) is the cellular homologue of the vmyc gene originally isolated from an avian myelocytomatosis virus. The cMyc protein is a transcription factor (nuclear localization). cMyc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of cMyc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclindependent kinase, ERK2 and CJun Nterminal Kinase (JNK) in cell proliferation and cell cycle regulation. In normal cells the expression of cMyc is tightly regulated but in human cancers cMyc is frequently deregulated. cMyc is also essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells.
  • Conjugation: Biotin
  • anti-CD138 / Syndecan 1 antibody [B-A38] (PE)
  • Cat. No: ARG54219  (Mouse mAb)
  • Reactivity: Hu
  • Application: FACS
  • Specificity: The antibody BA38 recognizes CD138 (syndecan 1), a heparan sulfate proteoglycan protein expressed mainly in the epidermis and plasma cells, but also in growth factorstimulated lymphocytes. The MWs of the glycosylated CD138 were variety, and MW of the non-glycosylated core protein (dimmer form) was around 60-80 kda.
  • Conjugation: PE
  • anti-CD135 / FLT3 antibody [BV10A4] (PE)
  • Cat. No: ARG54230  (Mouse mAb)
  • Reactivity: Hu
  • Application: FACS
  • Specificity: The mouse monoclonal antibody BV10A4 (BV10) reacts with CD135 (FLT3, FLK2, STK1), a 130160 kDa type III receptor tyrosine kinase that is involved in early steps of hematopoiesis.
  • Conjugation: PE
  • anti-Drebrin antibody [DBN-N-03] (PE)
  • Cat. No: ARG54239  (Mouse mAb)
  • Reactivity: Hu
  • Application: FACS
  • Specificity: The clone DBN-N-03 recognizes drebrin, an approximately 100-125 kDa regulator of actin cytoskeleton.
  • Conjugation: PE
  • anti-CD205 antibody [HD30] (PE)
  • Cat. No: ARG54254  (Mouse mAb)
  • Reactivity: Hu
  • Application: FACS
  • Specificity: The clone HD30 recognizes CD205, an approx. 200 kDa C-type lectin transmembrane protein of the MMR (macrophage mannose receptor) family, expressed at high levels on dendritic cells and thymic epithelial cells, and at low levels on lymphocytes, NK cells and monocytes.
  • Conjugation: PE
  • anti-CD25 antibody [MEM-181] (PerCP)
  • Cat. No: ARG54274  (Mouse mAb)
  • Reactivity: Hu
  • Application: FACS
  • Specificity: The clone MEM-181 reacts with CD25 (Interleukin-2 receptor alpha chain), a 55 kDa type I transmembrane glycoprotein expressed on activated B and T lymphocytes, activated monocytes/macrophages and on CD4+ T lymphocytes (T regulatory cells); it is lost on resting B and T lymphocytes.
    HLDA VI; WS Code NL N-L024
  • Conjugation: PerCP
  • anti-CD45RA antibody [MEM-56] (PE)
  • Cat. No: ARG54278  (Mouse mAb)
  • Reactivity: Hu
  • Application: FACS
  • Specificity: The clone MEM-56 reacts with CD45RA, a 205-220 kDa single chain type I glycoprotein, variant of CD45 (CD45RA isoform). CD45RA is expressed on most of B lymphocytes, resting and native T lymphocytes, medullar thymocytes and monocytes.
    HLDA IV; WS Code NL 907
  • Conjugation: PE
  • anti-CXCR6 / Bonzo antibody
  • Cat. No: ARG54407  (Rabbit pAb)
  • Reactivity: Hu
  • Application: WB
  • Specificity: This antibody recognizes full-length Bonzo (40 kD).
  • Conjugation: Un-conjugated