Programmed cell death (PCD)

Programmed cell death (PCD)


Programmed cell death (PCD) is a controlled process required for the maintenance of cellular homeostasis and elimination of unwanted cells including cancerous and infected cells. PCD includes apoptosis and non-apoptotic cell death. Apoptosis is the best-studied form of PCD with the characteristic of caspase activation. Non-apoptotic cell death can be triggered independently of apoptosis or function as a backup mechanism in case of the failure of apoptosis. The non-apoptotic forms of PCD includes necroptosis, pyroptosis, ferroptosis, etc. arigo offers quality antibodies to facilitate the research of programmed cell death.
 

- Apoptosis marker-

Caspase-3 (cleaved) antibody (ARG57512)

PARP (cleaved) antibody (ARG20041)


- Necroptosis marker-

RIP1 pSer166 antibody [YJY-1-5] (ARG66476

MLKL pSer358 antibody (ARG40184)


- Pyroptosis marker-

Pyroptosis Antibody Panel ARG30330)

● Includes antibodies against Caspase-1, GSDMD, and IL-1 beta.
● Detects both pro- and cleaved forms.
● Includes loading control.
● Works on human and mouse samples.

Conponent Reativily Application
Caspase-1 antibody Hu, Ms ICC/IF, IHC-P, IP, WB
GSDMD antibody Hu, Ms, Rat ICC/IF, WB
IL-1 beta antibody [SQab1748] Hu, Ms ELISA, FACS, ICC/IF, IHC-P, WB
beta-Tubulin antibody [BT7R] Hu, Ms, Rat, Ck, Mk, Rb ELISA, ICC/IF, WB



- Ferroptosis marker-

Ferroptosis/Oxytosis Antibody Panel (ARG30337)

● Includes molecular markers GPX4 and xCT antibodies.
● Includes the marker of lipid peroxidation.
● Works on humanmouse, and rat samples.

Conponent Reativily Application
GPX4 antibody Hu, Ms, Rat ICC/IF, IHC-P, WB
xCT antibody Hu, Ms, Rat IP, WB
4-HNE antibody [12F7]   ELISA, ICC/IF, WB



- Autophgy marker-

Autophagy antibody panel (ARG30321)

● Includes autophagy markers
● Includes loading control
● Includes secondary antibody
● Works on humanmouse, and rat samples

Conponen Reativily Application
LC3B antibody Hu, Ms, Rat, Pig ICC/IF, IHC-P, WB
SQSTM1 antibody Hu, Ms, Rat ICC/IF, IHC-P, IP, WB
Beclin-1 antibody Hu, Ms, Rat IHC-P, WB
GAPDH antibody [SQab1878] Hu, Ms, Rat, Bv, Ck, Mk, Pig, Xl, Zfsh FACS, ICC/IF, IHC-P, IP, WB
anti-Rabbit IgG antibody (HRP) Rb ELISA, IHC-P, WB