New antibody panels and duos for Tumor immune microenvironment (TIME)
New antibody panels and duos for Tumor immune microenvironment (TIME)
The infiltrating immune cells in tumor microenvironment have become a crucial point in cancer research due to their association with tumor progression and suppression. The anti-tumor immune responses involve cytotoxic T lymphocytes (CTLs) and NK cells for identifying and eliminating cancer cells. In contrast, the pro-cancer immune responses involves regulatory T cells (Tregs) and tumor-associated myeloid cells (e.g., MDSCs, TAMs etc.) for supporting tumor growth and suppressing anti-tumor immune responses. Current cancer immunotherapies focus on enhancing immune cells to recognize and destroy cancer cells. Targeting immunosuppressive cell subpopulations may pave the way for future therapies. arigo launches a series of antibody duos and panels for identifying tumor-infiltrating lymphocytes (TILs) (ARG30334), MDSCs (ARG30336 and ARG30335 for human and mouse respectively), M1/M2/TAMs (ARG30333), and CAF Marker Antibody Duo (ARG30322). These panels and duos are the best solution to characterize tumor immune microenvironment and facilitate the understanding of the clinical impact of tumor immune infiltration. |
Tumor-infiltrating Lymphocyte Antibody Panel (ARG30334) * Includes general T cell marker CD3 antibody. |
Component | Reactivity | Application | Package |
CD3 antibody [SQab1713] | Hu | FACS, ICC/IF, IHC-P, IP, WB | 20 μl |
CD8 antibody [SQab19146] | Hu | IHC-P | 20 μl |
CD4 antibody [SQab1714] | Hu | FACS, IHC-P, IP, WB | 20 μl |
CD20 antibody [SQab1719] | Hu | FACS, ICC/IF, IHC-P, IP | 20 μl |
M1/M2/TAM Marker Antibody Panel (ARG30333) * Includes the antibody markers for M1, M2, and TAMs. |
Component | Reactivity | Application | Package |
CD68 antibody [KP1] | Hu, Ms, Rat, Rb | FACS, ICC/IF, IHC-Fr, IHC-P, WB | 20 μg |
iNOS antibody | Hu, Ms, Rat, Mamm | ICC/IF, IHC-Fr, IHC-P, IP, WB | 50 μl |
CD163 antibody [SQab19148] | Hu | IHC-P | 20 μl |
CD206 antibody [15-2] | Hu, Ms | FACS, ICC/IF, IHC-Fr, IP, WB | 20 μg |
Human MDSC Marker Antibody Duo (ARG30336) * Includes the key MDSC marker antibodies. |
Product | Component | Reactivity | Application |
Human MDSC Marker Antibody Duo (ARG30336) |
CD11b antibody [M1/70] | Hu, Ms, Mk , Bb | FACS, ICC/IF, IHC-Fr, IP |
CD33 antibody [WM53] | Hu, NHuPrm | FACS, ICC/IF, IHC-Fr, IP, WB | |
CD11b antibody [M1/70] | Hu, Ms, Mk , Bb | FACS, ICC/IF, IHC-Fr, IP | |
Gr-1 antibody [RB6-8C5] | Ms | FACS, IHC-Fr, IHC-P, IP |
CAF Marker Antibody Panel (ARG30347) * Includes mesenchymal marker Vimentin antibody. |
Component | Reactivity | Application |
Vimentin antibody [SQab1721] | Hu, Ms | FACS, ICC/IF, IHC-Fr, IHC-P, IP, WB |
FAP-1 antibody | Hu, Ms, Rat | ICC/IF, IHC-P, WB |
alpha-SMA antibody [SQab18108] | Hu, Ms, Rat, Mk, Bv, Dog, Pig, Zfsh | FACS, ICC/IF, IHC-Fr, IHC-P, WB |
FAP antibody | Hu, Ms, Rat | ICC/IF, IHC-P, WB |