ARG30335
Mouse MDSC Marker Antibody Duo
Myeloid-derived suppressor cells marker; MDSCs marker; Tumor immune microenvironment; tumor-associated myeloid cells
Publication4
Component
| Cat No | Component Name | Host clonality | Reactivity | Application | Package |
|---|---|---|---|---|---|
| ARG22104 | anti-Ly6G + Ly6C antibody [RB6-8C5] | Rat mAb | Ms | Depletion, FACS, IHC-Fr, IHC-P, IP | 50 μg |
| ARG22000 | anti-CD11b antibody [M1/70] | Rat mAb | Hu, Ms, Bb, R. Mk | BL, FACS, ICC/IF, IHC-Fr, IP | 50 μg |
Overview
| Product Description | Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immune cells from the myeloid lineage. MDSCs are well-known key negative regulators of the immune response in tumor microenvironment. Accumulated evidences show that MDSCs may serve as a therapeutic target for preventing tumor progression.In mice, MDSCs are defined as cells expressing both CD11b and Gr-1 (Ly6G + Ly6C). arigo’s Mouse MDSC Marker Antibody Duo comprises CD11b and Gr-1 (Ly6G + Ly6C) antibodies. It is the best solution to identify the MDSCs in mouse tumor tissues. Related news: New antibody panels and duos for Tumor immune microenvironment Anti-SerpinB9 therapy, a new strategy for cancer therapy |
|---|---|
| Target Name | Mouse MDSC Marker |
| Alternate Names | Mouse MDSC Marker antibody; Myeloid-derived suppressor cells marker antibody; MDSCs marker antibody; CD11b antibody; Ly6G + Ly6C antibody |
Properties
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
|---|---|
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Full Name | Mouse Myeloid-derived suppressor cell (MDSC) marker Antibody Duo |
|---|---|
| Highlight | Related products: MDSC Duos / Panels; |
| Research Area | Myeloid-derived suppressor cells marker; MDSCs marker; Tumor immune microenvironment; tumor-associated myeloid cells |
Images (2) Click the Picture to Zoom In
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ARG22000 anti-CD11b antibody [M1/70] IHC-Fr image
Immunohistochemistry: Cryosection of Mouse lymph node stained with ARG22000 anti-CD11b antibody [M1/70] (green, A) and anti-Mouse CD8 antibody (red, B). Merged image in C.
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Specific References
Mac-1 deficiency ameliorates pressure overloaded heart failure through inhibiting macrophage polarization and activation
ARG22000: IHC-Fr, WB / Mouse
Integrin CD11b Contributes to Hypertension and Vascular Dysfunction Through Mediating Macrophage Adhesion and Migration
ARG22000:WB / Mouse
CD11b mediates hypertensive cardiac remodeling by regulating macrophage infiltration and polarization
Mouse / ARG22000: IHC-P, WB
Downregulation of AKT/mTOR signaling pathway for Salmonella-mediated autophagy in human anaplastic thyroid cancer
ARG22104: IHC-P / Mouse
