ARG24098
anti-CD273 / PD-L2 antibody
anti-CD273 / PD-L2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CD273 / PD-L2 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Predict Reactivity | Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CD273 / PD-L2 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide within amino acids 140-190 of CD273 / PD-L2. |
| Conjugation | Un-conjugated |
| Protein Full Name | Programmed cell death 1 ligand 2 |
| Alternate Names | B7DC; bA574F11.2; PDL2; CD antigen CD273; PD-L2; Programmed cell death 1 ligand 2; CD273; Btdc; PDCD1L2; Programmed death ligand 2; Butyrophilin B7-DC; B7-DC; PD-1 ligand 2; PDCD1 ligand 2 |
Application Instructions
| Application Suggestion |
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| Application Note | IHC-P: Antigen Retrieval:Heat mediated was performed using Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| Observed Size | ~30 - 50 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS and 0.02% Sodium azide |
| Preservative | 0.02% Sodium azide |
| Concentration | Batch dependent |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PDCD1LG2 |
| Gene Full Name | programmed cell death 1 ligand 2 |
| Function | Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity). [UniProt] |
| Cellular Localization | Cell membrane; Membrane; Secreted |
| Highlight | Related products: PD-L2 antibodies; PD-L2 ELISA Kits; Related news: The best solution for PD-1/PD-L1 research |
| Calculated MW | 31 kDa |
| PTM | Disulfide bond; Glycoprotein |
Images (3) Click the Picture to Zoom In
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ARG24098 anti-CD273 / PD-L2 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Mouse Brain stained with ARG24098 anti-CD273 / PD-L2 antibody at 1:250 dilution. Antigen Retrieval: Heat mediated was performed using citrate buffer (pH 6.0).
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ARG24098 anti-CD273 / PD-L2 antibody ICC/IF image
Immunofluorescence: Mouse brain were fixed with 4% PFA were stained with ARG24098 anti-CD273 / PD-L2 antibody at 1:500 dilution, overnight at 4°C.
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ARG24098 anti-CD273 / PD-L2 antibody WB image
Western blot: HeLa cell lysates stained with ARG24098 anti-CD273 / PD-L2 antibody.
