ARG24099
anti-CD273 / PD-L2 antibody [4E10]
anti-CD273 / PD-L2 antibody [4E10] for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Overview
| Product Description | Mouse Monoclonal antibody [4E10] recognizes CD273 / PD-L2 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Predict Reactivity | Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 4E10 |
| Isotype | IgG1 |
| Target Name | CD273 / PD-L2 |
| Antigen Species | Human |
| Immunogen | Recombinant protein fragment within extracellular domain of Human CD273/PD-L2. |
| Conjugation | Un-conjugated |
| Protein Full Name | Programmed cell death 1 ligand 2 |
| Alternate Names | B7DC; bA574F11.2; PDL2; CD antigen CD273; PD-L2; Programmed cell death 1 ligand 2; CD273; Btdc; PDCD1L2; Programmed death ligand 2; Butyrophilin B7-DC; B7-DC; PD-1 ligand 2; PDCD1 ligand 2 |
Application Instructions
| Application Suggestion |
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| Application Note | IHC-P: Antigen Retrieval:Heat mediated was performed using Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| Observed Size | ~30 - 50 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS, 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Concentration | Batch dependent |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PDCD1LG2 |
| Gene Full Name | programmed cell death 1 ligand 2 |
| Function | Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity). [UniProt] |
| Cellular Localization | Cell membrane; Membrane; Secreted |
| Highlight | Related products: PD-L2 antibodies; PD-L2 ELISA Kits; Related news: The best solution for PD-1/PD-L1 research |
| Calculated MW | 31 kDa |
| PTM | Disulfide bond; Glycoprotein |
Images (5) Click the Picture to Zoom In
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ARG24099 anti-CD273 / PD-L2 antibody [4E10] UHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human colon carcinoma stained with ARG24099 anti-CD273 / PD-L2 antibody [4E10].
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ARG24099 anti-CD273 / PD-L2 antibody [4E10] ICC/IF image
Immunofluorescence: Human colon tissue stained with ARG24099 anti-CD273 / PD-L2 antibody [4E10].
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ARG24099 anti-CD273 / PD-L2 antibody [4E10] FACS image
Flow Cytometry: HEK293 cells stained with ARG24099 anti-CD273 / PD-L2 antibody [4E10] (white). Unlabelled sample (gray) was used as a control.
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ARG24099 anti-CD273 / PD-L2 antibody [4E10] WB image
Western blot: HEK293 cells were stained with ARG24099 anti-CD273 / PD-L2 antibody [4E10].
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ARG24099 anti-CD273 / PD-L2 antibody [4E10] ICC/IF image
Immunofluorescence: HEK293 cells stained with ARG24099 anti-CD273 / PD-L2 antibody [4E10].
