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Search Result - Primary Antibodies

  • anti-Insulin antibody
  • Cat. No: ARG62502 　(Guinea pig pAb)
  • Reactivity: Hu, Ms, Rat, Hm
  • Application: FACS, ICC/IF, IHC-Fr, IHC-P, IP
  • Conjugation: Un-conjugated
  • anti-Myc tag antibody [9E10]
  • publication_list (1 Publications)
  • Cat. No: ARG62962 　(Mouse mAb)
  • Reactivity: Other
  • Application: FACS, IHC-P, IP, WB, CyTOF®-candidate
  • Specificity: The clone 9E10 may be used to detect the c-Myc tag.
    The c-myc gene (8q24 on human chromosome) is the cellular homologue of the v-myc gene originally isolated from an avian myelocytomatosis virus. The c-Myc protein is a transcription factor (nuclear localization). c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin-dependent kinase, ERK2 and C-Jun N-terminal Kinase (JNK) in cell proliferation and cell cycle regulation. In normal cells the expression of c-Myc is tightly regulated but in human cancers c-Myc is frequently deregulated. c-Myc is also essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells.
  • Conjugation: Un-conjugated
  • anti-p53 antibody [BP53-12]
  • Cat. No: ARG63081 　(Mouse mAb)
  • Reactivity: Hu, NHuPrm
  • Application: ELISA, FACS, ICC/IF, IHC-P, IP, WB
  • Specificity: The clone BP53-12 recognizes defined epitope (aa 16-25) on human p53, a 50 kDa tumour suppressor found in increased amounts in a wide variety of transformed cells; it is frequently mutated or inactivated in many types of cancer.
  • Conjugation: Un-conjugated
  • anti-Ki-67 antibody [Ki-67]
  • Cat. No: ARG65620 　(Mouse mAb)
  • Reactivity: Hu, Bov
  • Application: FACS, ICC/IF, IHC, WB, CyTOF®-candidate
  • Specificity: This antibody recognizes Ki-67 antigen, a non-histone nuclear protein expressed exclusively in proliferating cells.
  • Conjugation: Un-conjugated
  • anti-CD44 antibody [IM7]
  • Cat. No: ARG65642 　(Rat mAb)
  • Reactivity: Hu, Ms, Cat, Dog, Hrs
  • Application: FACS, ICC/IF, IHC-Fr, IHC-P, IP, WB, CyTOF®-candidate
  • Specificity: Reacts with CD44 antigen (Phagocyte glycoprotein 1), an 80-95 kDa transmembrane glycoprotein (hyaladherin family) present on the most of cells and tissues (leukocytes, endothelial cells, mesenchymal cells, etc.); it is negative on platelets and hepatocytes. The antibody reacts with all isoforms of mouse CD44.
  • Conjugation: Un-conjugated
  • anti-PUMA antibody
  • Cat. No: ARG57486 　(Rabbit pAb)
  • Reactivity: Hu, Ms, Rat
  • Application: FACS, ICC/IF, IHC-P, WB
  • Specificity: This antibody detects endogenous levels of total PUMA.
  • Conjugation: Un-conjugated
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