ARG41454
anti-serum Amyloid A antibody
anti-serum Amyloid A antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes serum Amyloid A |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | serum Amyloid A |
| Antigen Species | Human |
| Immunogen | Synthetic peptide of Human serum Amyloid A. |
| Conjugation | Un-conjugated |
| Alternate Names | 2-104; 2-103; 2-102; Serum amyloid A-1 protein; TP53I4; SAA; Amyloid fibril protein AA; SAA2; PIG4; 4-101; 3-104 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Human plasma | ||||||
| Observed Size | ~ 12 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SAA1 |
| Gene Full Name | serum amyloid A1 |
| Background | This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Jun 2012] |
| Function | Major acute phase protein. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Calculated MW | 14 kDa |
| PTM | This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 24 residues from the C-terminal end. [UniProt] |
Images (2) Click the Picture to Zoom In
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ARG41454 anti-serum Amyloid A antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human liver cancer tissue stained with ARG41454 anti-serum Amyloid A antibody.
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ARG41454 anti-serum Amyloid A antibody WB image
Western blot: Human plasma lysate stained with ARG41454 anti-serum Amyloid A antibody.
