ARG40180
anti-YTHDF3 antibody
anti-YTHDF3 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes YTHDF3 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, IP, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | YTHDF3 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-275 of Human YTHDF3 (NP_689971.4). |
| Conjugation | Un-conjugated |
| Alternate Names | YTH domain-containing family protein 3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Positive Control | HepG2 | ||||||||||
| Observed Size | 64 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q7Z739 Human YTH domain-containing family protein 3 Swiss-port # Q8BYK6 Mouse YTH domain-containing family protein 3 |
|---|---|
| Gene Symbol | YTHDF3 |
| Gene Full Name | YTH N(6)-methyladenosine RNA binding protein 3 |
| Background | This gene encodes a member of the YTH (YT521-B homology) domain protein family. The YTH domain is common in eukaryotes, is often found in the middle of the protein sequence, and may function in binding to RNA. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013] |
| Function | Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. [UniProt] |
| Cellular Localization | Cytoplasm, cytosol. [UniProt] |
| Calculated MW | 64 kDa |
Images (3) Click the Picture to Zoom In
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ARG40180 anti-YTHDF3 antibody ICC/IF image
Immunofluorescence: U2OS cells stained with ARG40180 anti-YTHDF3 antibody at 1:100 dilution.
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ARG40180 anti-YTHDF3 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse stomach stained with ARG40180 anti-YTHDF3 antibody at 1:100 dilution.
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ARG40180 anti-YTHDF3 antibody WB image
Western blot: 25 ug of HepG2 cell lysate stained with ARG40180 anti-YTHDF3 antibody at 1:1000 dilution.
