ARG41717
anti-TRIM31 antibody
anti-TRIM31 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TRIM31 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TRIM31 |
| Antigen Species | Human |
| Immunogen | Fusion protein of Human TRIM31. |
| Conjugation | Un-conjugated |
| Alternate Names | EC 6.3.2.-; E3 ubiquitin-protein ligase TRIM31; Tripartite motif-containing protein 31; RNF; HCGI; HCG1; C6orf13 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | WB: Human kidney IHC-P: Human esophagus cancer |
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| Observed Size | ~ 50 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 40% Glycerol |
| Concentration | 0.2 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9BZY9 Human E3 ubiquitin-protein ligase TRIM31 |
|---|---|
| Gene Symbol | TRIM31 |
| Gene Full Name | tripartite motif containing 31 |
| Background | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to both the cytoplasm and the nucleus. Its function has not been identified. [provided by RefSeq, Jul 2008] |
| Function | Regulator of Src-induced anchorage independent cell growth (By similarity). May have E3 ubiquitin-protein ligase activity. [UniProt] |
| Cellular Localization | Cytoplasm. Mitochondrion. Note=Predominantly expressed in the cytoplasm but a fraction is associated with the mitochondria. [UniProt] |
| Calculated MW | 48 kDa |
| PTM | Auto-ubiquitinated (in vitro). [UniProt] |
Images (2) Click the Picture to Zoom In
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ARG41717 anti-TRIM31 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human esophagus cancer tissue stained with ARG41717 anti-TRIM31 antibody (left) at 1:20 dilution, or the same antibody pre-incubated with fusion protein (right). (Original magnification: X200).
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ARG41717 anti-TRIM31 antibody WB image
Western blot: 40 µg of Human kidney lysate stained with ARG41717 anti-TRIM31 antibody at 1:300 dilution.
