ARG63844
anti-TPH2 antibody
anti-TPH2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse
Neuroscience antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes TPH2 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Predict Reactivity | Cow, Dog, Pig |
| Tested Application | ICC/IF, IHC-P |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TPH2 |
| Antigen Species | Human |
| Immunogen | C-NKPNSGKNDDKGNK |
| Conjugation | Un-conjugated |
| Alternate Names | Tryptophan 5-hydroxylase 2; ADHD7; NTPH; Neuronal tryptophan hydroxylase; Tryptophan 5-monooxygenase 2; EC 1.14.16.4 |
Application Instructions
| Application Suggestion |
|
||||||
|---|---|---|---|---|---|---|---|
| Application Note | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Background | This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. [provided by RefSeq, Jul 2008] |
| Research Area | Neuroscience antibody |
| Calculated MW | 56 kDa |
Images (1) Click the Picture to Zoom In
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ARG63844 anti-TPH2 antibody IHC-P image
Immunohistochemistry: Paraffin embedded Human Brain Stem. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63844 anti-TPH2 antibody at 4 µg/ml dilution followed by HRP-staining.
