ARG63819
anti-TGIF2 antibody
anti-TGIF2 antibody for Western blot and Human
Cancer antibody; Gene Regulation antibody
Overview
Product Description | Goat Polyclonal antibody recognizes TGIF2 |
---|---|
Tested Reactivity | Hu |
Predict Reactivity | Ms, Rat, Dog, Pig |
Tested Application | WB |
Host | Goat |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | TGIF2 |
Antigen Species | Human |
Immunogen | C-EMELQKQQDP |
Conjugation | Un-conjugated |
Alternate Names | Homeobox protein TGIF2; TGFB-induced factor 2; 5'-TG-3'-interacting factor 2; TGF-beta-induced transcription factor 2 |
Application Instructions
Application Suggestion |
|
||||
---|---|---|---|---|---|
Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
---|---|
Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
Preservative | 0.02% Sodium azide |
Stabilizer | 0.5% BSA |
Concentration | 0.5 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
---|---|
Background | The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and over-expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read-through transcription also exists between this gene and the neighboring downstream C20orf24 (chromosome 20 open reading frame 24) gene. [provided by RefSeq, Dec 2010] |
Research Area | Cancer antibody; Gene Regulation antibody |
Calculated MW | 26 kDa |
PTM | The C-terminal part is phosphorylated in response to EGF signaling by the Ras/MAPK pathway. |
Images (1) Click the Picture to Zoom In