ARG42910

anti-Syndecan 3 antibody

anti-Syndecan 3 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes Syndecan 3
Tested Reactivity Hu, Rat
Predict Reactivity Ms, Hm
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name Syndecan 3
Antigen Species Mouse
Immunogen Synthetic peptide corresponding to aa. 45-60 of Mouse Syndecan 3. (AQRWRNENFERPVDLE)
Conjugation Un-conjugated
Alternate Names Syndecan-3; SYND3; SDCN

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:200 - 1:1000
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size ~ 55 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer 0.2% Na2HPO4, 0.9% NaCl, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA.
Preservative 0.05% Thimerosal and 0.05% Sodium azide
Stabilizer 5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 116673 Rat SDC3

GeneID: 9672 Human SDC3

Swiss-port # O75056 Human Syndecan-3

Swiss-port # P33671 Rat Syndecan-3

Gene Symbol SDC3
Gene Full Name syndecan 3
Background The protein encoded by this gene belongs to the syndecan proteoglycan family. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. Allelic variants of this gene have been associated with obesity. [provided by RefSeq, Oct 2009]
Function Cell surface proteoglycan that may bear heparan sulfate (By similarity). May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. [UniProt]
Cellular Localization Membrane; Single-pass type I membrane protein. [UniProt]
Calculated MW 46 kDa
PTM O-glycosylated within the Thr/Ser-rich region which could interact with lectin domains on other molecules. [UniProt]

Images (3) Click the Picture to Zoom In

  • ARG42910 anti-Syndecan 3 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human placenta tissue stained with ARG42910 anti-Syndecan 3 antibody.

  • ARG42910 anti-Syndecan 3 antibody WB image

    Western blot: U-87 MG, 293T, PC-12, NRK and HT1080 cell lysates stained with ARG42910 anti-Syndecan 3 antibody.

  • ARG42910 anti-Syndecan 3 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Rat brain tissue stained with ARG42910 anti-Syndecan 3 antibody.