ARG45291
anti-Surf1 antibody
anti-Surf1 antibody for Flow cytometry,ICC/IF,Western blot and Human,Mouse,Rat,Monkey
Overview
| Product Description | Polyclonal antibody recognizes Surf1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat, Mk |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Surf1 |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human Surf1. |
| Conjugation | Un-conjugated |
| Alternate Names | SURF1; SURF1 Cytochrome C Oxidase Assembly Factor; Surfeit Locus Protein 1; SHY1; Surfeit 1; MC4DN1; SURF-1; CMT4K |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Observed Size | 33 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SURF1 |
| Gene Full Name | SURF1 Cytochrome C Oxidase Assembly Factor |
| Background | This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. [provided by RefSeq, Jul 2008] |
| Function | Component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly.. [UniProt] |
| Cellular Localization | Mitochondrion inner membrane. [UniProt] |
| Calculated MW | 28 kDa |
Images (6) Click the Picture to Zoom In
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ARG45291 anti-Surf1 antibody ICC/IF image
Immunofluorescence: T47D stained with ARG45291 anti-Surf1 antibody at 5 ug/ml dilution.
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ARG45291 anti-Surf1 antibody WB image
Western blot: Hela and 293T stained with ARG45291 anti-Surf1 antibody at 0.5 μg/ml dilution.
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ARG45291 anti-Surf1 antibody FACS image
Flow Cytometry: Jurkat stained with ARG45291 anti-Surf1 antibody at 1 µg/10^6 cells dilution.
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ARG45291 anti-Surf1 antibody WB image
Western blot: Rat heart and rat kidney stained with ARG45291 anti-Surf1 antibody at 0.5 μg/ml dilution.
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ARG45291 anti-Surf1 antibody WB image
Western blot: Mouse heart and mouse kidney stained with ARG45291 anti-Surf1 antibody at 0.5 μg/ml dilution.
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ARG45291 anti-Surf1 antibody WB image
Western blot: COS-7 stained with ARG45291 anti-Surf1 antibody at 0.5 μg/ml dilution.
