ARG59865

anti-SUCLG1 antibody

anti-SUCLG1 antibody for ICC/IF,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes SUCLG1
Tested Reactivity Hu, Ms, Rat
Tested Application ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name SUCLG1
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 41-346 of Human SUCLG1 (NP_003840.2).
Conjugation Un-conjugated
Alternate Names EC 6.2.1.5; SCS-alpha; SUCLA1; MTDPS9; Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; EC 6.2.1.4; Succinyl-CoA synthetase subunit alpha; GALPHA

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:50 - 1:200
WB1:200 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Rat liver, Mouse heart and A-549
Observed Size 26 - 36 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 114597 Rat SUCLG1

GeneID: 56451 Mouse SUCLG1

GeneID: 8802 Human SUCLG1

Gene Symbol SUCLG1
Gene Full Name succinate-CoA ligase, alpha subunit
Background This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion. [provided by RefSeq, Feb 2010]
Function Catalyzes the ATP- or GTP-dependent ligation of succinate and CoA to form succinyl-CoA. The nature of the beta subunit determines the nucleotide specificity (By similarity). [UniProt]
Cellular Localization Mitochondrion. [UniProt]
Calculated MW 36 kDa

Images (1) Click the Picture to Zoom In

  • ARG59865 anti-SUCLG1 antibody WB image

    Western blot: 25 µg of Rat liver, Mouse heart and A549 cell lysates stained with ARG59865 anti-SUCLG1 antibody at 1:1000 dilution.