ARG40109

anti-STC1 / Stanniocalcin 1 antibody

anti-STC1 / Stanniocalcin 1 antibody for Western blot and Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes STC1 / Stanniocalcin 1
Tested Reactivity Ms, Rat
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name STC1 / Stanniocalcin 1
Antigen Species Human
Immunogen Recombinant protein of Human STC1.
Conjugation Un-conjugated
Alternate Names Stanniocalcin-1; STC-1; STC

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:1000 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Rat kidney and Mouse kidney
Observed Size ~ 28 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 20855 Mouse STC1

GeneID: 81801 Rat STC1

Swiss-port # O55183 Mouse Stanniocalcin-1

Swiss-port # P97574 Rat Stanniocalcin-1

Gene Symbol STC1
Gene Full Name stanniocalcin 1
Background This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers. [provided by RefSeq, Jul 2008]
Function Stimulates renal phosphate reabsorption, and could therefore prevent hypercalcemia. [UniProt]
Cellular Localization Secreted. [UniProt]
Calculated MW 28 kDa

Images (1) Click the Picture to Zoom In

  • ARG40109 anti-STC1 / Stanniocalcin 1 antibody WB image

    Western blot: 25 µg of Rat kidney and Mouse kidney lysates stained with ARG40109 anti-STC1 / Stanniocalcin 1 antibody at 1:1000 dilution.