ARG55530
anti-SHMT1 antibody
anti-SHMT1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Metabolism antibody; Signaling Transduction antibody
Overview
Product Description | Rabbit Polyclonal antibody recognizes SHMT1 |
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Tested Reactivity | Hu |
Predict Reactivity | Bov |
Tested Application | IHC-P, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | SHMT1 |
Antigen Species | Human |
Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 19-47 (N-terminus) of Human SHMT1. |
Conjugation | Un-conjugated |
Alternate Names | EC 2.1.2.1; SHMT; CSHMT; Serine methylase; Glycine hydroxymethyltransferase; Serine hydroxymethyltransferase, cytosolic |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
Positive Control | 293 |
Properties
Form | Liquid |
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Purification | Purification with Protein A and immunogen peptide |
Buffer | PBS and 0.09% (W/V) Sodium azide |
Preservative | 0.09% (W/V) Sodium azide |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # P34896 Human Serine hydroxymethyltransferase, cytosolic |
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Gene Symbol | SHMT1 |
Gene Full Name | serine hydroxymethyltransferase 1 (soluble) |
Background | This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |
Function | Interconversion of serine and glycine. [UniProt] |
Research Area | Metabolism antibody; Signaling Transduction antibody |
Calculated MW | 53 kDa |
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