ARG57119
anti-SAR1B / SARA2 antibody [1C7]
anti-SAR1B / SARA2 antibody [1C7] for Flow cytometry,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [1C7] recognizes SAR1B / SARA2 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 1C7 |
| Isotype | IgG1, kappa |
| Target Name | SAR1B / SARA2 |
| Antigen Species | Human |
| Immunogen | Recombinant fragment around aa. 1-198 of Human SAR1B / SARA2 |
| Conjugation | Un-conjugated |
| Alternate Names | ANDD; GTP-binding protein SAR1b; GTP-binding protein B; CMRD; SARA2; GTBPB |
Application Instructions
| Application Suggestion |
|
||||||
|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 10% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SAR1B |
| Gene Full Name | secretion associated, Ras related GTPase 1B |
| Background | The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010] |
| Function | Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex. [UniProt] |
| Calculated MW | 22 kDa |
Images (2) Click the Picture to Zoom In
-
ARG57119 anti-SAR1B / SARA2 antibody [1C7] FACS image
Flow Cytometry: Hep3B cell line stained with ARG57119 anti-SAR1B / SARA2 antibody [1C7] at 2-5 µg for 1x10^6 cells (red line). Secondary antibody: Goat anti-Mouse IgG Alexa fluor 488 conjugate. Isotype control antibody: Mouse IgG (black line).
-
ARG57119 anti-SAR1B / SARA2 antibody [1C7] WB image
Western blot: 40 µg of Mouse muscle lysate stained with ARG57119 anti-SAR1B / SARA2 antibody [1C7] at 1:1000.
