ARG44237
anti-RTN4IP1 antibody
anti-RTN4IP1 antibody for Flow cytometry,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes RTN4IP1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | RTN4IP1 |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human RTN4IP1 |
| Conjugation | Un-conjugated |
| Protein Full Name | Reticulon-4-interacting protein 1, mitochondrial |
| Alternate Names | RTN4IP1; Reticulon 4 Interacting Protein 1; NIMP; Reticulon-4-Interacting Protein 1, Mitochondrial; NOGO-Interacting Mitochondrial Protein; OPA10 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8WWV3 Human Reticulon-4-interacting protein 1, mitochondrial Swiss-port # Q924D0 Mouse Reticulon-4-interacting protein 1, mitochondrial |
|---|---|
| Gene Symbol | RTN4IP1 |
| Gene Full Name | Reticulon 4 Interacting Protein 1 |
| Background | This gene encodes a mitochondrial protein that interacts with reticulon 4, which is a potent inhibitor of regeneration following spinal cord injury. This interaction may be important for reticulon-induced inhibition of neurite growth. Mutations in this gene can cause optic atrophy 10, with or without ataxia, cognitive disability, and seizures. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants. |
| Function | Plays a role in the regulation of retinal ganglion cell (RGC) neurite outgrowth, and hence in the development of the inner retina and optic nerve. Appears to be a potent inhibitor of regeneration following spinal cord injury. |
| Calculated MW | 44 kDa |
| PTM | Membrane, Mitochondrion, Mitochondrion outer membrane |
Images (3) Click the Picture to Zoom In
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ARG44237 anti-RTN4IP1 antibody FACS image
Flow Cytometry: K562 stained with ARG44237 anti-RTN4IP1 antibody at 1 μg/1x10^6 cells dilution.
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ARG44237 anti-RTN4IP1 antibody WB image
Western blot: Rat liver and Rat kidney stained with ARG44237 anti-RTN4IP1 antibody at 0.5 μg/mL dilution.
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ARG44237 anti-RTN4IP1 antibody WB image
Western blot: Mouse liver and Mouse kidney stained with ARG44237 anti-RTN4IP1 antibody at 0.5 μg/mL dilution.
