ARG52406
anti-RAB3 antibody
anti-RAB3 antibody for Western blot and Rat
Signaling Transduction antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes RAB3 |
|---|---|
| Tested Reactivity | Rat |
| Predict Reactivity | Hu, Ms, NHuPrm, Xenopus laevis |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | RAB3 |
| Antigen Species | Rat |
| Immunogen | Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH |
| Conjugation | Un-conjugated |
| Alternate Names | Ras-related protein Rab-3A |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | Specific for ~27k Rab3 protein. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity Purified |
| Buffer | 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol |
| Stabilizer | 0.1 mg/ml BSA, 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | RAB3A |
| Gene Full Name | RAB3A, member RAS oncogene family |
| Background | Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms: 3A, 3B, 3C, and 3D (Schluter et al., 2004). These proteins are expressed in highest concentrations in brain and endocrine tissues and involved in regulated exocytosis of hormones and neurotransmitters (Coppola et al., 2002). Specifically, Rab3’s are thought to play a key role in presynaptic vesicle trafficking and priming (Schluter et al., 2006). |
| Research Area | Signaling Transduction antibody |
| Calculated MW | 25 kDa |
Images (1) Click the Picture to Zoom In
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ARG52406 anti-RAB3 antibody WB image
Western blot: Rat cortex lysate stained with ARG52406 anti-RAB3 antibody showing specific labeling of the ~27k Rab3 protein.
