ARG63947

anti-PRODH antibody

anti-PRODH antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody; Metabolism antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes PRODH
Tested Reactivity Hu
Predict Reactivity Ms
Tested Application IHC-P, WB
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name PRODH
Antigen Species Human
Immunogen C-ERDGSGTNKRDKQYQ
Conjugation Un-conjugated
Alternate Names TP53I6; Proline oxidase 2; POX; EC 1.5.5.2; PRODH1; PRODH2; HSPOX2; p53-induced gene 6 protein; PIG6; Proline dehydrogenase 1, mitochondrial; Proline oxidase

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P3 - 5 µg/ml
WBAssay - dependent
Application Note WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 5625 Human PRODH

Swiss-port # O43272 Human Proline dehydrogenase 1, mitochondrial

Background This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010]
Research Area Cancer antibody; Cell Biology and Cellular Response antibody; Cell Death antibody; Metabolism antibody; Signaling Transduction antibody
Calculated MW 68 kDa

Images (3) Click the Picture to Zoom In

  • ARG63947 anti-PRODH antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human liver tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63947 anti-PRODH antibody at 3.75 µg/ml dilution followed by AP-staining.

  • ARG63947 anti-PRODH antibody IHC-P image

    Immunohistochemistry: paraffin embedded Human Cerebellum. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63947 anti-PRODH antibody at 3.8 µg/ml dilution followed by AP-staining.

  • ARG63947 anti-PRODH antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human colon tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63947 anti-PRODH antibody at 3.75 µg/ml dilution followed by AP-staining.