ARG57072
anti-PGD antibody [46B3]
anti-PGD antibody [46B3] for Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [46B3] recognizes PGD |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 46B3 |
| Isotype | IgG2b, kappa |
| Target Name | PGD |
| Antigen Species | Human |
| Immunogen | Recombinant fragment around aa. 1-483 of Human PGD. |
| Conjugation | Un-conjugated |
| Alternate Names | 6PGD; 6-phosphogluconate dehydrogenase, decarboxylating; EC 1.1.1.44 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 10% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P52209 Human 6-phosphogluconate dehydrogenase, decarboxylating |
|---|---|
| Gene Symbol | PGD |
| Gene Full Name | phosphogluconate dehydrogenase |
| Background | 6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015] |
| Function | Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. [UniProt] |
| Calculated MW | 53 kDa |
Images (1) Click the Picture to Zoom In
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ARG57072 anti-PGD antibody [46B3] WB image
Western blot: 40 µg of 1) HeLa cell lysate, 2) MCF7 cell lysate, 3) 293T cell lysate, 4) A549 cell lysate, 5) Jurkat cell lysate stained with ARG57072 anti-PGD antibody [46B3] at 1:1000.
