ARG42234
anti-NPTX2 antibody
anti-NPTX2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes NPTX2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NPTX2 |
| Antigen Species | Human |
| Immunogen | A 16 amino acid peptide within aa. 170-220 of Human NPTX2. |
| Conjugation | Un-conjugated |
| Alternate Names | Neuronal pentraxin II; Neuronal pentraxin-2; NP-II; NARP; NP2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | 43 ~ 47 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | NPTX2 |
| Gene Full Name | neuronal pentraxin II |
| Background | This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq, Feb 2009] |
| Function | Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner (By similarity). [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Calculated MW | 47 kDa |
Images (6) Click the Picture to Zoom In
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ARG42234 anti-NPTX2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse brain tissue. Tissue was fixed with formaldehyde and blocked with 10% serum for 1 hour at RT. Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0). The tissue section was stained with ARG42234 anti-NPTX2 antibody at 5 µg/ml dilution, overnight at 4°C.
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ARG42234 anti-NPTX2 antibody WB image
Western blot: 15 µg of Mouse brain lysate stained with ARG42234 anti-NPTX2 antibody at 0.5 or 1 µg/ml dilution and incubated at RT for 1 hour, in 5% NFDM/TBST.
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ARG42234 anti-NPTX2 antibody IHC-P image
Immunohistochemistry: 4% Paraformaldehyde-fixed Mouse brain tissue stained with ARG42234 anti-NPTX2 antibody (red) at 20 µg/ml dilution. DAPI (blue) for nuclear staining.
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ARG42234 anti-NPTX2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human brain tissue. Tissue was fixed with formaldehyde and blocked with 10% serum for 1 hour at RT. Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0). The tissue section was stained with ARG42234 anti-NPTX2 antibody at 5 µg/ml dilution, overnight at 4°C.
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ARG42234 anti-NPTX2 antibody IHC-P image
Immunohistochemistry: 4% Paraformaldehyde-fixed Human brain tissue stained with ARG42234 anti-NPTX2 antibody at 20 µg/ml dilution.
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ARG42234 anti-NPTX2 antibody WB image
Western blot: 15 µg of 293, A431, A549, CaCo-2, Daudi, HeLa, HepG2, K562, MCF-7, Jurkat, SK-N-SH, THP-1, NIH/3T3 and YB2/0 cell lysates stained with ARG42234 anti-NPTX2 antibody at 2 µg/ml dilution and incubated at RT for 1 hour, in 5% NFDM/TBST.
