ARG42233
anti-NPTX1 / NP1 antibody
anti-NPTX1 / NP1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Goat Polyclonal antibody recognizes NPTX1 / NP1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NPTX1 / NP1 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around the internal region of Human NPTX1 / NP1. (C-ERVKIETALTSLHQR) (NP_002513.2) |
| Conjugation | Un-conjugated |
| Alternate Names | Neuronal pentraxin-1; NP-I; NP1; Neuronal pentraxin I |
Application Instructions
| Application Suggestion |
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| Application Note | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| Positive Control | Human frontal cortex | ||||||
| Observed Size | ~ 50 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Ammonium sulphate precipitation followed by affinity purification with immunogen. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | NPTX1 |
| Gene Full Name | neuronal pentraxin I |
| Background | NPTX1 is a member of the neuronal pentraxin gene family. Neuronal pentraxin 1 is similar to the rat NP1 gene which encodes a binding protein for the snake venom toxin taipoxin. Human NPTX1 mRNA is exclusively localized to the nervous system. [provided by RefSeq, Jul 2008] |
| Function | May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses. [UniProt] |
| Cellular Localization | Cytoplasmic vesicle, secretory vesicle. [UniProt] |
| Calculated MW | 47 kDa |
Images (2) Click the Picture to Zoom In
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ARG42233 anti-NPTX1 / NP1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human cerebellum tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG42233 anti-NPTX1 / NP1 antibody at 5 µg/ml dilution followed by AP-staining.
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ARG42233 anti-NPTX1 / NP1 antibody WB image
Western blot: 35 µg of Human frontal cortex lysate (in RIPA buffer) stained with ARG42233 anti-NPTX1 / NP1 antibody at 1 µg/ml dilution and incubated at RT for 1 hour.
