ARG42221
anti-NPTX1 / NP1 antibody
anti-NPTX1 / NP1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes NPTX1 / NP1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NPTX1 / NP1 |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide between aa. 322-350 of Human NPTX1 / NP1. |
| Conjugation | Un-conjugated |
| Alternate Names | Neuronal pentraxin-1; NP-I; NP1; Neuronal pentraxin I |
Application Instructions
| Application Suggestion |
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| Application Note | IHC-P: Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| Positive Control | Human brain | ||||||
| Observed Size | ~ 50 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A and immunogen peptide. |
| Buffer | PBS and 0.09% (W/V) Sodium azide. |
| Preservative | 0.09% (W/V) Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | NPTX1 |
| Gene Full Name | neuronal pentraxin I |
| Background | NPTX1 is a member of the neuronal pentraxin gene family. Neuronal pentraxin 1 is similar to the rat NP1 gene which encodes a binding protein for the snake venom toxin taipoxin. Human NPTX1 mRNA is exclusively localized to the nervous system. [provided by RefSeq, Jul 2008] |
| Function | May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses. [UniProt] |
| Cellular Localization | Cytoplasmic vesicle, secretory vesicle. [UniProt] |
| Calculated MW | 47 kDa |
Images (2) Click the Picture to Zoom In
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ARG42221 anti-NPTX1 / NP1 antibody IHC-P image
Immunohistochemistry: Paraformaldehyde-fixed and paraffin-embedded Human brain tissue section. Tissue was blocked with 3% BSA for 0.5 hour at room temperature. Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0). Samples were stained with ARG42221 anti-NPTX1 / NP1 antibody at 1:25 dilution for 1 hour at 37°C.
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ARG42221 anti-NPTX1 / NP1 antibody WB image
Western blot: 20 µg of Human brain lysate stained with ARG42221 anti-NPTX1 / NP1 antibody at 1:2000 dilution.
