ARG65701
anti-NBR1 antibody
anti-NBR1 antibody for ICC/IF,Western blot and Human,Mouse,Rat
Cell Biology and Cellular Response antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes NBR1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | NBR1 |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human NBR1. |
| Conjugation | Un-conjugated |
| Alternate Names | Protein 1A1-3B; Neighbor of BRCA1 gene 1 protein; Membrane component chromosome 17 surface marker 2; Cell migration-inducing gene 19 protein; M17S2; IAI3B; Next to BRCA1 gene 1 protein; MIG19; 1A1-3B |
Application Instructions
| Predict Reactivity Note | Monkey, Rat | ||||||
|---|---|---|---|---|---|---|---|
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | HeLa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | NBR1 |
| Gene Full Name | neighbor of BRCA1 gene 1 |
| Background | The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014] |
| Function | Acts probably as a receptor for selective autophagosomal degradation of ubiquitinated targets. [UniProt] |
| Research Area | Cell Biology and Cellular Response antibody |
| Calculated MW | 107 kDa |
Images (3) Click the Picture to Zoom In
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ARG65701 anti-NBR1 antibody ICC/IF image
Immunofluorescence: NIH/3T3 stained with ARG65701 anti-NBR1 antibody at 1:50 dilution.
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ARG65701 anti-NBR1 antibody WB image
Western blot: HeLa and 293F stained with ARG65701 anti-NBR1 antibody at 1:400 dilution.
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ARG65701 anti-NBR1 antibody ICC/IF image
Immunofluorescence: PC-12 stained with ARG65701 anti-NBR1 antibody at 1:50 dilution.
