ARG45394
anti-MICS1 / GHITM antibody
anti-MICS1 / GHITM antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes MICS1 / GHITM |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | MICS1 / GHITM |
| Antigen Species | Human |
| Immunogen | Recombinant protein containing to human MICS1 / GHITM. |
| Conjugation | Un-conjugated |
| Alternate Names | Dermal papilla-derived protein 2; MICS1; PTD010; HSPC282; My021; Transmembrane BAX inhibitor motif-containing protein 5; DERP2; TMBIM5; Growth hormone-inducible transmembrane protein; Mitochondrial morphology and cristae structure 1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Observed Size | 37 kDa |
Properties
| Form | Powder |
|---|---|
| Purification | Affinity purified |
| Buffer | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | GHITM |
| Gene Full Name | growth hormone inducible transmembrane protein |
| Background | Enables calcium:proton antiporter activity. Involved in calcium export from the mitochondrion; inner mitochondrial membrane organization; and negative regulation of release of cytochrome c from mitochondria. Located in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Nov 2024] |
| Function | Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c. [UniProt] |
| Cellular Localization | Mitochondrion inner membrane. [UniProt] |
| Calculated MW | 37 kDa |
| PTM | Plays an important role in maintenance of mitochondrial morphology and in mediating either calcium or potassium/proton antiport. [UniProt] |
Images (7) Click the Picture to Zoom In
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ARG45394 anti-MICS1 / GHITM antibody IHC-P image
Immunohistochemistry: Human liver cancer stained with ARG45394 anti-MICS1 / GHITM antibody at 2 μg/ml dilution.
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ARG45394 anti-MICS1 / GHITM antibody ICC/IF image
Immunofluorescence: HEP3B stained with ARG45394 anti-MICS1 / GHITM antibody at 5 μg/ml dilution.
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ARG45394 anti-MICS1 / GHITM antibody WB image
Western blot: Hela stained with ARG45394 anti-MICS1 / GHITM antibody at 0.5 μg/ml dilution.
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ARG45394 anti-MICS1 / GHITM antibody FACS image
Flow Cytometry: A431 stained with ARG45394 anti-MICS1 / GHITM antibody at 1 µg/10^6 cells dilution.
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ARG45394 anti-MICS1 / GHITM antibody IHC-P image
Immunohistochemistry: Rat testis stained with ARG45394 anti-MICS1 / GHITM antibody at 2 μg/ml dilution.
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ARG45394 anti-MICS1 / GHITM antibody WB image
Western blot: Rat testis stained with ARG45394 anti-MICS1 / GHITM antibody at 0.5 μg/ml dilution.
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ARG45394 anti-MICS1 / GHITM antibody WB image
Western blot: Mouse testis stained with ARG45394 anti-MICS1 / GHITM antibody at 0.5 μg/ml dilution.
