ARG10825
anti-MAG antibody
anti-MAG antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Overview
Product Description | Rabbit Polyclonal antibody recognizes MAG |
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Tested Reactivity | Hu, Ms, Rat |
Predict Reactivity | Dog, Mk, Rb |
Tested Application | IHC-P, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | MAG |
Antigen Species | Human |
Immunogen | aa. 114-132 (KYYFRGDLGGYNQYTFSEH) (100% homologous in Human, Mouse and Rat). |
Conjugation | Un-conjugated |
Alternate Names | GMA; Myelin-associated glycoprotein; SIGLEC4A; S-MAG; Siglec-4a; SIGLEC-4A |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Affinity purification with immunogen. |
Buffer | PBS, 0.025% Sodium azide and 2.5% BSA. |
Preservative | 0.025% Sodium azide |
Stabilizer | 2.5% BSA |
Concentration | 0.5 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | MAG |
Gene Full Name | myelin associated glycoprotein |
Background | The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2010] |
Function | Adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. Preferentially binds to alpha-2,3-linked sialic acid (By similarity). [UniProt] |
Calculated MW | 60-100 kDa (glycosylated) |
PTM | N-glycosylated. Phosphorylated on tyrosine residues. |
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