ARG44413

anti-LRIT3 antibody

anti-LRIT3 antibody for ICC/IF,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes LRIT3
Tested Reactivity Hu, Ms, Rat
Tested Application ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Target Name LRIT3
Antigen Species Human
Immunogen Human LRIT3 recombinant protein (aa. sequence: E50-R573).
Conjugation Un-conjugated
Alternate Names LRIT3; Leucine Rich Repeat, Ig-Like And Transmembrane Domains 3; FIGLER4; CSNB1F; Leucine-Rich Repeat, Immunoglobulin-Like Domain And Transmembrane Domain-Containing Protein 3; Fibronectin Type III, Immunoglobulin And Leucine Rich Repeat Domains 4

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF5 µg/ml
WB0.25-0.5 µg/ml
Application Note The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose.
Preservative 0.05% Sodium azide
Stabilizer 4% Trehalose
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.

Bioinformation

Database Links

GeneID: 345193 Human LRIT3

Swiss-port # Q3SXY7 Human Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-c

Gene Symbol LRIT3
Gene Full Name Leucine Rich Repeat, Ig-Like And Transmembrane Domains 3
Background This gene encodes a protein that has a fibronectin type III domain and a C-terminal transmembrane domain, as well as a leucine-rich repeat domain and immunoglobulin-like domain near the N-terminus. The encoded protein may regulate fibroblast growth factor receptors and affect the modification of these receptors, which are glycosylated differently in the Golgi and endoplasmic reticulum. Mutations in this gene are associated with congenital stationary night blindness, type 1F.
Function Plays a role in the synapse formation and synaptic transmission between cone photoreceptor cells and retinal bipolar cells.
Cellular Localization Cell projection, Endoplasmic reticulum, Membrane
Calculated MW 75 kDa
PTM Disulfide bond, Glycoprotein

Images (4) Click the Picture to Zoom In

  • ARG44413 anti-LRIT3 antibody ICC/IF image

    Immunofluorescence: U2OS stained with ARG44413 anti-LRIT3 antibody at 5 μg/mL dilution.

  • ARG44413 anti-LRIT3 antibody WB image

    Western blot: 293T and Jurkat stained with ARG44413 anti-LRIT3 antibody at 0.5 μg/mL dilution.

  • ARG44413 anti-LRIT3 antibody WB image

    Western blot: Rat kidney stained with ARG44413 anti-LRIT3 antibody at 0.5 μg/mL dilution.

  • ARG44413 anti-LRIT3 antibody WB image

    Western blot: Mouse kidney stained with ARG44413 anti-LRIT3 antibody at 0.5 μg/mL dilution.