ARG63624
anti-LNK / SH2B3 antibody
anti-LNK / SH2B3 antibody for Western blot and Human
Immune System antibody; Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes LNK / SH2B3 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | LNK / SH2B3 |
| Antigen Species | Human |
| Immunogen | NGPALQPSSPC |
| Conjugation | Un-conjugated |
| Alternate Names | Lymphocyte-specific adapter protein Lnk; LNK; SH2B adapter protein 3; Signal transduction protein Lnk; IDDM20; Lymphocyte adapter protein |
Application Instructions
| Application Suggestion |
|
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Background | This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus.[provided by RefSeq, May 2010] |
| Research Area | Immune System antibody; Signaling Transduction antibody |
| Calculated MW | 63 kDa |
| PTM | Tyrosine phosphorylated by LCK. |
Images (2) Click the Picture to Zoom In
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ARG63624 anti-LNK / SH2B3 antibody WB image
Western Blot: MOLT4 lysate (35 µg protein in RIPA buffer) stained with ARG63624 anti-LNK / SH2B3 antibody at 0.3 µg/ml dilution.
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ARG63624 anti-LNK / SH2B3 antibody WB image
Western Blot: 1). Mock transfection; 2) SH2B3 (RC218359) expressing plasmid transfected HEK293 cell lysate standed with ARG63624 anti-LNK / SH2B3 antibody
