ARG65789
anti-KLF2 antibody
anti-KLF2 antibody for Western blot and Human
Overview
| Product Description | Goat Polyclonal antibody recognizes KLF2 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat, Cow, Dog, Pig |
| Tested Application | WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | KLF2 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide around the N-terminus of Human KLF2 protein (NP_057354.1). (ALSEPILPSFST-C) |
| Conjugation | Un-conjugated |
| Alternate Names | LKLF; Krueppel-like factor 2; Lung krueppel-like factor |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | KLF2 |
| Gene Full Name | Kruppel-like factor 2 |
| Background | Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1; MIM 601974) and the selectin CD62L (SELL; MIM 153240) (summary by Weinreich et al., 2009 [PubMed 19592277]).[supplied by OMIM, Feb 2011] |
| Function | Binds to the CACCC box in the beta-globin gene promoter and activates transcription. [UniProt] |
| Calculated MW | 37.4 kDa (NP_057354.1) |
| PTM | Ubiquitinated. Polyubiquitination involves WWP1 and leads to proteasomal degradation of this protein (By similarity). |
Images (1) Click the Picture to Zoom In
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ARG65789 anti-KLF2 antibody WB image
Western blot: 35 µg of Human heart (A) and lung (B) lysates stained with ARG65789 anti-KLF2 antibody at 1 µg/ml dilution (1 hour).
