ARG40362
anti-ITIH1 antibody
anti-ITIH1 antibody for Flow cytometry,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes ITIH1 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | ITIH1 |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide between aa. 606-635 of Human ITIH1. |
| Conjugation | Un-conjugated |
| Alternate Names | ITIH; Inter-alpha-trypsin inhibitor complex component III; SHAP; Inter-alpha-inhibitor heavy chain 1; Serum-derived hyaluronan-associated protein; H1P; ITI-HC1; Inter-alpha-trypsin inhibitor heavy chain H1; IATIH; ITI heavy chain H1; IGHEP1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Human plasma |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A and immunogen peptide. |
| Buffer | PBS and 0.09% (W/V) Sodium azide. |
| Preservative | 0.09% (W/V) Sodium azide. |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P19827 Human Inter-alpha-trypsin inhibitor heavy chain H1 |
|---|---|
| Gene Symbol | ITIH1 |
| Gene Full Name | inter-alpha-trypsin inhibitor heavy chain 1 |
| Background | The protein encoded by this gene is the heavy chain of a serine protease inhibitor that may serve to carry hyaluronan in plasma. This gene is part of a cluster of similar genes on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009] |
| Function | May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. Contains a potential peptide which could stimulate a broad spectrum of phagocytotic cells. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Calculated MW | 101 kDa |
| PTM | Heavy chains are linked to bikunin via chondroitin 4-sulfate esterified to the alpha-carboxyl of the C-terminal aspartate after propeptide cleavage. The S-linked glycan is composed of two 6-carbon sugars, possibly Glc or Gal. [UniProt] |
Images (2) Click the Picture to Zoom In
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ARG40362 anti-ITIH1 antibody WB image
Western blot: 20 µg of Human plasma lysate stained with ARG40362 anti-ITIH1 antibody at 1:1000 dilution.
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ARG40362 anti-ITIH1 antibody FACS image
Flow Cytometry: HL-60 cells stained with ARG40362 anti-ITIH1 antibody (right histogram) or without primary antibody as control (left histogram), followed by incubation with FITC labelled secondary antibody.
