ARG44483
anti-INTU antibody
anti-INTU antibody for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes INTU |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | INTU |
| Antigen Species | Human |
| Immunogen | Human INTU recombinant protein |
| Conjugation | Un-conjugated |
| Alternate Names | INTU; Inturned Planar Cell Polarity Protein; KIAA1284; CPLANE4; PDZD6; PDZK6; Ciliogenesis And Planar Polarity Effector Complex Subunit 4; Inturned Planar Cell Polarity Effector Homolog; PDZ Domain-Containing Protein 6; PDZ Domain Containing 6; Protein Inturned; Inturned Planar Cell Polarity Effector Homolog (Drosophila); Ciliogenesis And Planar Polarity Effector 4; SRTD20; OFD17; INT |
Application Instructions
| Application Suggestion |
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| Application Note | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 4% Trehalose |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | INTU |
| Gene Full Name | Inturned Planar Cell Polarity Protein |
| Background | Involved in embryonic digit morphogenesis; roof of mouth development; and tongue morphogenesis. Located in ciliary basal body and motile cilium. Implicated in asphyxiating thoracic dystrophy and orofaciodigital syndrome XVII. |
| Function | Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling. |
| Cellular Localization | Cell projection, Cytoplasm, Cytoskeleton |
| Calculated MW | 106 kDa |
| PTM | Phosphoprotein |
Images (3) Click the Picture to Zoom In
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ARG44483 anti-INTU antibody IHC-P image
Immunohistochemistry: Human prostate cancer stained with ARG44483 anti-INTU antibody at 2 μg/mL dilution.
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ARG44483 anti-INTU antibody WB image
Western blot: SiHa and A431 stained with ARG44483 anti-INTU antibody at 0.5 μg/mL dilution.
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ARG44483 anti-INTU antibody FACS image
Flow Cytometry: MCF-7 stained with ARG44483 anti-INTU antibody at 1 μg/10^6 cells dilution.
