ARG56836
anti-IFN beta antibody
anti-IFN beta antibody for ELISA,IHC-Formalin-fixed paraffin-embedded sections,Neutralizing,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes IFN beta |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, IHC-P, Neut, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | IFN beta |
| Antigen Species | Human |
| Immunogen | E.coli derived recombinant Human Interferon beta. (MSYNLLGFLQ RSSNFQCQKL LWQLNGRLEY CLKDRMNFDI PEEIKQLQQF QKEDAALTIY EMLQNIFAIF RQDSSSTGWN ETIVENLLAN VYHQINHLKT VLEEKLEKED FTRGKLMSSL HLKRYYGRIL HYLKAKEYSH CAWTIVRVEI LRNFYFINRL TGYLRN) |
| Conjugation | Un-conjugated |
| Alternate Names | Fibroblast interferon; IFN-beta; IFNB; IFF; IFB; Interferon beta |
Application Instructions
| Application Suggestion |
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| Application Note | IHC-P: Antigen Retrieval: Boil tissue section in Sodium citrate buffer (pH 6.0) followed by cooling at RT for 20 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.2) |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | IFNB1 |
| Gene Full Name | interferon, beta 1, fibroblast |
| Background | This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection. [provided by RefSeq, Sep 2015] |
| Function | Has antiviral, antibacterial and anticancer activities. [UniProt] |
| Highlight | Related products: IFN beta antibodies; IFN beta ELISA Kits; IFN beta recombinant proteins; Anti-Rabbit IgG secondary antibodies; Related news: Exploring Antiviral Immune Response circNDUFB2, a circular RNA (circRNA), activates anti-tumor immunity |
| Calculated MW | 22 kDa |
Images (3) Click the Picture to Zoom In
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ARG56836 anti-IFN beta antibody WB image
Western blot: 250 - 0.24 ng of Human IFN-beta stained with ARG56836 anti-IFN beta antibody, under non-reducing conditions.
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ARG56836 anti-IFN beta antibody standard curve image
Sandwich ELISA: ARG56836 anti-IFN beta antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with anti-Interferon beta antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density reading at 405 - 650 nm.
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ARG56836 anti-IFN beta antibody WB image
Western blot: 250 - 0.24 ng of Human IFN-beta stained with ARG56836 anti-IFN beta antibody, under reducing conditions.
