circNDUFB2, a circular RNA (circRNA), activates anti-tumor immunity

Circular RNA (circRNA) is a type of covalently closed single-stranded RNA that has been linked to cancer progression. Li et al. reported that circNDUFB2 inhibits growth and metastasis of NSCLC cells. Moreover, circNDUFB2 also triggers type I interferon signaling and activates immune defense response in NSCLC cells. arigo is proud that our IFN beta, CXCL10, CXCL11, and CCL5 ELISA kits were used to demonstrate that type I interferon signaling is activated by circNDUFB2.

Target	Human	Mouse	Rat
IFN alpha	ARG80156	ARG82282	ARG80951
IFN beta	ARG81244	ARG82317	ARG81377
CCL5 / RANTES	ARG80155	ARG80210	ARG80244
CXCL10 / IP-10	ARG80181	ARG80220
CXCL11 / I-TAC	ARG81444	ARG82060