ARG63936
anti-HRS / HGS antibody
anti-HRS / HGS antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Cell Biology and Cellular Response antibody; Signaling Transduction antibody
Overview
Product Description | Goat Polyclonal antibody recognizes HRS / HGS |
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Tested Reactivity | Hu |
Predict Reactivity | Ms, Rat, Dog |
Tested Application | IHC-P, WB |
Host | Goat |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | HRS / HGS |
Antigen Species | Human |
Immunogen | C-NRNYWEKKQEEARK |
Conjugation | Un-conjugated |
Alternate Names | Protein pp110; Hrs; Hepatocyte growth factor-regulated tyrosine kinase substrate; HRS |
Application Instructions
Application Suggestion |
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Application Note | IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
Preservative | 0.02% Sodium azide |
Stabilizer | 0.5% BSA |
Concentration | 0.5 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # O14964 Human Hepatocyte growth factor-regulated tyrosine kinase substrate |
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Background | The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [provided by RefSeq, Dec 2010] |
Highlight | Related products: Hrs antibodies; Hrs ELISA Kits; Anti-Goat IgG secondary antibodies; Related news: Detecting exosomal PD-L1 secreted by cancer cells |
Research Area | Cell Biology and Cellular Response antibody; Signaling Transduction antibody |
Calculated MW | 86 kDa |
PTM | Phosphorylated on Tyr-334. A minor site of phosphorylation on Tyr-329 is detected (By similarity). Phosphorylation occurs in response to EGF, IL-2, GM-CSF and HGF. Ubiquitinated by ITCH. |
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