ARG63936

anti-HRS / HGS antibody

anti-HRS / HGS antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Cell Biology and Cellular Response antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes HRS / HGS
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Dog
Tested Application IHC-P, WB
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name HRS / HGS
Antigen Species Human
Immunogen C-NRNYWEKKQEEARK
Conjugation Un-conjugated
Alternate Names Protein pp110; Hrs; Hepatocyte growth factor-regulated tyrosine kinase substrate; HRS

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1 - 2 µg/ml
WBAssay-dependent
Application Note IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 9146 Human HGS

Swiss-port # O14964 Human Hepatocyte growth factor-regulated tyrosine kinase substrate

Background The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [provided by RefSeq, Dec 2010]
Highlight Related products:
Hrs antibodies; Hrs ELISA Kits; Anti-Goat IgG secondary antibodies;
Related news:
Detecting exosomal PD-L1 secreted by cancer cells
Research Area Cell Biology and Cellular Response antibody; Signaling Transduction antibody
Calculated MW 86 kDa
PTM Phosphorylated on Tyr-334. A minor site of phosphorylation on Tyr-329 is detected (By similarity). Phosphorylation occurs in response to EGF, IL-2, GM-CSF and HGF.
Ubiquitinated by ITCH.

Images (1) Click the Picture to Zoom In

  • ARG63936 anti-HRS / HGS antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human testis tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63936 anti-HRS / HGS antibody at 2.5 µg/ml dilution followed by AP-staining.