ARG63556

anti-GCIP / MAID antibody

anti-GCIP / MAID antibody for IHC-Formalin-fixed paraffin-embedded sections and Human

Cell Biology and Cellular Response antibody; Controls and Markers antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes GCIP / MAID
Tested Reactivity Hu
Predict Reactivity Dog
Tested Application IHC-P
Specificity This antibody is expected to recognise both human isoforms of this protein.
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name GCIP / MAID
Antigen Species Human
Immunogen C-NRIKELTQSELEL
Conjugation Un-conjugated
Alternate Names DIP1; Grap2 and cyclin-D-interacting protein; GCIP; Cyclin-D1-binding protein 1; HHM; Human homolog of Maid

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P3 - 6 µg/ml
Application Note IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 23582 Human CCNDBP1

Swiss-port # O95273 Human Cyclin-D1-binding protein 1

Background This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene. [provided by RefSeq, Apr 2009]
Research Area Cell Biology and Cellular Response antibody; Controls and Markers antibody; Signaling Transduction antibody
Calculated MW 40 kDa
PTM Phosphorylated.

Images (1) Click the Picture to Zoom In

  • ARG63556 anti-GCIP / MAID antibody IHC-P image

    Immunohistochemistry: paraffin embedded Human Prostate. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63556 anti-CCNDBP1 antibody at 3.8 µg/ml dilution followed by AP-staining.