ARG59801
anti-EFTUD2 antibody
anti-EFTUD2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes EFTUD2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, IP, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | EFTUD2 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-205 of Human EFTUD2 (NP_004238.3). |
| Conjugation | Un-conjugated |
| Alternate Names | Snrp116; 116 kDa U5 small nuclear ribonucleoprotein component; Snu114; U5-116 kDa; U5-116KD; Elongation factor Tu GTP-binding domain-containing protein 2; MFDGA; U5 snRNP-specific protein, 116 kDa; SNU114 homolog; SNRNP116; MFDM; hSNU114 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
| Positive Control | Mouse spleen and HeLa | ||||||||||
| Observed Size | 120 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O08810 Mouse 116 kDa U5 small nuclear ribonucleoprotein component Swiss-port # Q15029 Human 116 kDa U5 small nuclear ribonucleoprotein component |
|---|---|
| Gene Symbol | EFTUD2 |
| Gene Full Name | elongation factor Tu GTP binding domain containing 2 |
| Background | This gene encodes a GTPase which is a component of the spliceosome complex which processes precursor mRNAs to produce mature mRNAs. Mutations in this gene are associated with mandibulofacial dysostosis with microcephaly. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |
| Function | Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex required for pre-mRNA splicing. Binds GTP. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 109 kDa |
Images (5) Click the Picture to Zoom In
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ARG59801 anti-EFTUD2 antibody ICC/IF image
Immunofluorescence: U2OS cells stained with ARG59801 anti-EFTUD2 antibody.
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ARG59801 anti-EFTUD2 antibody WB image
Western blot: 25 µg of Mouse spleen and HeLa cell lysates stained with ARG59801 anti-EFTUD2 antibody at 1:2000 dilution.
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ARG59801 anti-EFTUD2 antibody IP image
Immunoprecipitation: 100 µg extracts of 293T cells immunoprecipitated and stained with ARG59801 anti-EFTUD2 antibody at 1:1000 dilution.
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ARG59801 anti-EFTUD2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat liver stained with ARG59801 anti-EFTUD2 antibody at 1:100 dilution.
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ARG59801 anti-EFTUD2 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse kidney stained with ARG59801 anti-EFTUD2 antibody at 1:100 dilution.
