ARG57076
anti-Cystatin A antibody [1B12]
anti-Cystatin A antibody [1B12] for Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody [1B12] recognizes Cystatin A |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 1B12 |
| Isotype | IgG1, kappa |
| Target Name | Cystatin A |
| Antigen Species | Human |
| Immunogen | Recombinant fragment around aa. 1-98 of Human Cystatin A. |
| Conjugation | Un-conjugated |
| Alternate Names | STFA; Cystatin-A; AREI; STF1; Cystatin-AS; Stefin-A |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 10% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CSTA |
| Gene Full Name | cystatin A (stefin A) |
| Background | The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer. [provided by RefSeq, Jul 2008] |
| Function | This is an intracellular thiol proteinase inhibitor. Has an important role in desmosome-mediated cell-cell adhesion in the lower levels of the epidermis. [UniProt] |
| Calculated MW | 11 kDa |
Images (1) Click the Picture to Zoom In
-
ARG57076 anti-Cystatin A antibody [1B12] WB image
Western blot: 40 µg of 1) A431 cell lysate, 2) THP1 cell lysate stained with ARG57076 anti-Cystatin A antibody [1B12] at 1:1000.
