ARG59925

anti-CXXC1 antibody

anti-CXXC1 antibody for ICC/IF,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes CXXC1
Tested Reactivity Hu, Ms, Rat
Tested Application ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name CXXC1
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 1-210 of Human CXXC1 (NP_001095124.1).
Conjugation Un-conjugated
Alternate Names 5830420C16Rik; CFP1; HsT2645; PHF18; 2410002I16Rik; CGBP; ZCGPC1; SPP1; hCGBP; PCCX1; CXXC-type zinc finger protein 1; CpG-binding protein; PHD finger and CXXC domain-containing protein 1

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Rat testis and HepG2
Observed Size 75 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 30827 Human CXXC1

GeneID: 74322 Mouse CXXC1

Swiss-port # Q9CWW7 Mouse CXXC-type zinc finger protein 1

Swiss-port # Q9P0U4 Human CXXC-type zinc finger protein 1

Gene Symbol CXXC1
Gene Full Name CXXC finger protein 1
Background This gene encodes a protein that functions as a transcriptional activator that binds specifically to non-methylated CpG motifs through its CXXC domain. The protein is a component of the SETD1 complex, regulates gene expression and is essential for vertebrate development. [provided by RefSeq, Sep 2015]
Function Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG. [UniProt]
Cellular Localization Nucleus speckle. Note=Associated with euchromatin. During mitosis, excluded from condensed chromosomes. [UniProt]
Calculated MW 76 kDa
PTM May be regulated by proteolysis. [UniProt]

Images (2) Click the Picture to Zoom In

  • ARG59925 anti-CXXC1 antibody ICC/IF image

    Immunofluorescence: A549 cells stained with ARG59925 anti-CXXC1 antibody.

  • ARG59925 anti-CXXC1 antibody WB image

    Western blot: 25 µg of Rat testis and HepG2 cell lysates stained with ARG59925 anti-CXXC1 antibody at 1:1000 dilution.