ARG45344
anti-CXCL16 antibody [15Q2]
anti-CXCL16 antibody [15Q2] for IHC-Formalin-fixed paraffin-embedded sections and Mouse
Overview
| Product Description | Rat Monoclonal antibody [15Q2] recognizes CXCL16 |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | IHC-P |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | 15Q2 |
| Isotype | IgG2 |
| Target Name | CXCL16 |
| Antigen Species | Mouse |
| Immunogen | Recombinant Mouse CXCL16. |
| Conjugation | Un-conjugated |
| Alternate Names | Transmembrane chemokine CXCL16; CXCLG16; C-X-C motif chemokine 16; SRPSOX; Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein; SR-PSOX; Small-inducible cytokine B16 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Powder |
|---|---|
| Purification | Protein G/A chromatography |
| Buffer | PBS |
| Reconstitution | PBS |
| Concentration | 0.2 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | Cxcl16 |
| Gene Full Name | chemokine (C-X-C motif) ligand 16 |
| Background | Enables chemokine activity. Involved in several processes, including positive regulation of cell growth; response to tumor necrosis factor; and response to type II interferon. Located in extracellular space. Biomarker of COVID-19 and systemic scleroderma. [provided by Alliance of Genome Resources, Nov 2024] |
| Function | Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. Also acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis. [UniProt] |
| Cellular Localization | Membrane. [UniProt] |
| Calculated MW | 28 kDa |
| PTM | Disulfide bond; Glycoprotein. [UniProt] |
Images (1) Click the Picture to Zoom In
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ARG45344 anti-CXCL16 antibody [15Q2] IHC-P image
Immunohistochemistry: Mouse kidney stained with ARG45344 anti-CXCL16 antibody [15Q2].
