ARG56746
anti-CXCL1 / GRO alpha antibody (Biotin)
anti-CXCL1 / GRO alpha antibody (Biotin) for ELISA,Western blot and Mouse
Overview
| Product Description | Biotin-conjugated Rabbit Polyclonal antibody recognizes CXCL1 / GRO alpha |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | ELISA, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CXCL1 / GRO alpha |
| Antigen Species | Mouse |
| Immunogen | E.coli derived Recombinant Mouse CXCL1. (APIANELRCQ CLQTMAGIHL KNIQSLKVLP SGPHCTQTEV IATLKNGREA CLDPEAPLVQ KIVQKMLKGV PK) |
| Conjugation | Biotin |
| Alternate Names | Growth-regulated alpha protein; SCYB1; Melanoma growth stimulatory activity; MGSA-a; GRO-alpha; GROa; NAP-3; FSP; C-X-C motif chemokine 1; Neutrophil-activating protein 3; GRO1; MGSA; IL-8 homologues (murine) |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified by affinity chromatography. |
| Buffer | PBS (pH 7.2) |
| Concentration | 1 mg/ml |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CXCL1 |
| Gene Full Name | C-X-C motif chemokine ligand 1 |
| Background | This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014] |
| Function | Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity. [UniProt] |
| Calculated MW | 11 kDa |
| PTM | N-terminal processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) are produced by proteolytic cleavage after secretion from peripheral blood monocytes. [UniProt] |
Images (2) Click the Picture to Zoom In
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ARG56746 anti-CXCL1 / GRO alpha antibody (Biotin) standard curve image
Direct ELISA: ARG56746 anti-CXCL1 / GRO alpha antibody (Biotin) at 0.25 - 1.0 µg/ml results of a typical standard run with optical density.
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ARG56746 anti-CXCL1 / GRO alpha antibody (Biotin) standard curve image
Sandwich ELISA: ARG56746 anti-CXCL1 / GRO alpha antibody (Biotin) as a detection antibody at 0.25 - 1.0 µg/ml combined with ARG56636 anti-CXCL1 (GRO alpha) antibody as a capture antibody. Results of a typical standard run with optical density.
