ARG54338
anti-CIDE B antibody
anti-CIDE B antibody for Western blot and Mouse
Cell Biology and Cellular Response antibody; Cell Death antibody; Gene Regulation antibody; Metabolism antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CIDE B |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | WB |
| Specificity | This antibody recognizes mouse CIDE-B (25kDa) and does not cross-react with CIDE-A. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CIDE B |
| Antigen Species | Mouse |
| Immunogen | Peptide corresponding to aa 204-219 of mouse CIDE-B (accession no. AF041377). |
| Conjugation | Un-conjugated |
| Alternate Names | Cell death-inducing DFFA-like effector B; Cell death activator CIDE-B |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Mouse liver |
Properties
| Form | Liquid |
|---|---|
| Purification | Immunoaffinity chroma-tography |
| Buffer | PBS (pH 7.4) and 0.02% Sodium azide |
| Preservative | 0.02% Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | Cideb |
| Gene Full Name | cell death-inducing DNA fragmentation factor, alpha subunit-like effector B |
| Background | DFF45-related proteins CIDE-A and CIDE-B have recently been identified. CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE-B induces apoptosis, which is inhibited by DFF45. CIDE-B is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-B is expressed mainly in liver and at lower levels in spleen, kidney, peripheral blood lymphocytes, and bone marrow. |
| Function | Activates apoptosis. [UniProt] |
| Research Area | Cell Biology and Cellular Response antibody; Cell Death antibody; Gene Regulation antibody; Metabolism antibody |
| Calculated MW | 25 kDa |
Images (1) Click the Picture to Zoom In
-
ARG54338 anti-CIDE B antibody WB image
Western blot: murine liver tissue stained with ARG54338 anti-CIDE B antibody at 2 μg/ml dilution.
