ARG55406
anti-CD73 antibody [AD2] (PE)
anti-CD73 antibody [AD2] (PE) for Flow cytometry and Human
Cell Biology and Cellular Response antibody
Overview
| Product Description | PE-conjugated Mouse Monoclonal antibody [AD2] recognizes CD73 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS |
| Specificity | The mouse monoclonal antibody AD2 recognizes CD73, a 70 kDa GPI-anchored 5'-nucleotidase expressed predominantly on T and B cell subsets, follicular dendritic cells and endothelial cells. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | AD2 |
| Isotype | IgG1 |
| Target Name | CD73 |
| Antigen Species | Human |
| Immunogen | Human CD73 protein |
| Conjugation | PE |
| Alternate Names | 5'-nucleotidase; CD antigen CD73; eN; CALJA; CD73; EC 3.1.3.5; NT; Ecto-5'-nucleotidase; NT5; E5NT; 5'-NT; eNT; NTE |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Purification | Affinity purification with immunogen. |
|---|---|
| Buffer | PBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA |
| Preservative | 15 mM Sodium azide |
| Stabilizer | 0.2% (w/v) high-grade protease free BSA |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | NT5E |
| Gene Full Name | 5'-nucleotidase, ecto (CD73) |
| Background | The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011] |
| Function | Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities. [UniProt] |
| Highlight | Related products: CD73 antibodies; Anti-Mouse IgG secondary antibodies; Related news: Stem cell and the regenerative medicine: Ready for the patients |
| Research Area | Cell Biology and Cellular Response antibody |
| Calculated MW | 63 kDa |
Images (3) Click the Picture to Zoom In
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ARG55406 anti-CD73 antibody [AD2] (PE) FACS image
Flow Cytometry: Human peripheral whole blood stained with ARG55406 anti-CD73 antibody [AD2] (PE) (10 µl reagent / 100 µl of peripheral whole blood).
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ARG55406 anti-CD73 antibody [AD2] (PE) FACS image
Flow Cytometry: Human lymphocytes stained with ARG55406 anti-CD73 antibody [AD2] (PE) (10 µl reagent / 100 µl of peripheral whole blood) and ARG53782 anti-CD19 antibody [LT19] (APC) (10 µl reagent / 100 µl of peripheral whole blood).
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ARG55406 anti-CD73 antibody [AD2] (PE) FACS image
Flow Cytometry: Separation of human CD73 positive B cells (red-filled) from CD73 negative CD19 negative lymphocytes (black-dashed). Human peripheral whole blood stained with ARG55406 anti-CD73 antibody [AD2] (PE) (10 µl reagent / 100 µl of peripheral whole blood).
