ARG30231
Phospho Ezrin Antibody Duo (Total, pT567)
Cancer antibody; Signaling Transduction antibody
Component
| Cat No | Component Name | Host clonality | Reactivity | Application | Package |
|---|---|---|---|---|---|
| ARG51694 | anti-Ezrin phospho (Thr567) antibody | Rabbit pAb | Hu, Ms, Rat | WB | 50 μl |
| ARG63968 | anti-Ezrin antibody | Goat pAb | Hu | IHC-P, WB | 50 μg |
Overview
| Product Description | Ezrin, also known as cytovillin or villin-2, belongs to ERM protein family that serves as intermediate between the plasma membrane and the actin cytoskeleton. It plays a key role in cell surface structure adhesion, migration, and organization. Phosphorylation of Ezrin has been functionally linked to acid secretion and vesicle recruitment to the apical secretory membrane in gastric parietal cells. Phosphorylation of the conserved T567 residue of ezrin has been shown to alter the N/C oligomerization of Ezrin and promote the formation of actin-rich surface projections in other cells. Zhu et al. 2007. Am J Physiol Cell Physiol 283(3): 874 Zhou et al. 2005. J Cell Sci 118: 4381 |
|---|---|
| Target Name | Ezrin |
| Alternate Names | Phospho Ezrin antibody; Ezrin phospho (Thr567) antibody; Ezrin antibody |
Properties
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
|---|---|
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Full Name | Phospho Ezrin Antibody Duo (Total, pT567) |
|---|---|
| Research Area | Cancer antibody; Signaling Transduction antibody |
Images (4) Click the Picture to Zoom In
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ARG63968 anti-Ezrin antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human kidney tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63968 anti-Ezrin antibody at 3.75 µg/ml dilution followed by AP-staining.
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ARG51694 anti-Ezrin phospho (Thr567) antibody WB image
Western Blot: extracts from MDA cells untreated or treated with anisomycin stained with anti-Ezrin (phospho Thr567) antibody ARG51694.
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ARG63968 anti-Ezrin / villin 2 antibody WB image
Western Blot: Human Placenta lysate (35 µg protein in RIPA buffer) stained with ARG63968 anti-Ezrin / villin 2 antibody at 1 µg/ml dilution.
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ARG63968 anti-Ezrin / villin 2 antibody IHC-P image
Immunohistochemistry: paraffin embedded Human Small Intestine. (Steamed antigen retrieval with citrate buffer pH 6) stained with ARG63968 anti-Ezrin / villin 2 antibody at 3.8 µg/ml dilution followed by AP-staining.
