ARG83283
Human Factor XI ELISA Kit
Human Factor XI ELISA Kit for ELISA and Human
Overview
| Product Description | ARG83283 Human Factor XI ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Factor XI in Serum, Plasma and Cell culture supernatants. |
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| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Specificity | There is no detectable cross-reactivity with other relevant proteins. |
| Target Name | Factor XI |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Sensitivity | 25 pg/ml |
| Detection Range | 0.78 ng/ml - 50 ng/ml |
| Sample Type | Serum, Plasma and Cell culture supernatants |
| Precision | Intra-Assay CV: 4.8% Inter-Assay CV: 5.2% |
| Alternate Names | F11; Coagulation Factor XI; FXI; Plasma Thromboplastin Antecedent; PTA; Coagualtion Factor XI; EC 3.4.21.27; EC 3.4.21 |
Application Instructions
| Assay Time | ~ 5 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | F11 |
| Gene Full Name | Coagulation Factor XI |
| Background | This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. |
| Function | Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX. |
| Cellular Localization | Secreted |
| PTM | Disulfide bond, Glycoprotein |
Images (1) Click the Picture to Zoom In
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ARG83283 Human Factor XI ELISA standard curve image
ARG83283 Human Factor XI ELISA results of a typical standard run with optical density reading at 450 nm.
| Title | Download Link |
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| ARG83283 Human Factor XI ELISA User manual |
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