ARG82966
Human CXCL11 / I-TAC ELISA Kit
Human CXCL11 / I-TAC ELISA Kit for ELISA and Human
Overview
| Product Description | ARG82966 Human CXCL11 / I-TAC ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human CXCL11 / I-TAC in serum, plasma and cell culture supernatants. |
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| Tested Reactivity | Hu |
| Tested Application | ELISA |
| Target Name | CXCL11 / I-TAC |
| Conjugation | HRP |
| Conjugation Note | Substrate: TMB and read at 450 nm. |
| Protein Full Name | C-X-C motif chemokine 11 |
| Sensitivity | 3.9 pg/ml |
| Sample Type | Serum, plasma and cell culture supernatants. |
| Standard Range | 7.8 - 500 pg/ml |
| Sample Volume | 100 μl |
| Precision | Intra-Assay CV: less than 10% Inter-Assay CV: less than 10% |
| Alternate Names | SCYB9B; SCYB11; C-X-C motif chemokine 11; Beta-R1; b-R1; Interferon gamma-inducible protein 9; I-TAC; Small-inducible cytokine B11; Interferon-inducible T-cell alpha chemoattractant; H174; IP-9; IP9 |
Application Instructions
| Assay Time | ~ 3.5 hours |
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Properties
| Form | 96 well |
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| Storage Instruction | Store the kit at 4°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CXCL11 |
| Gene Full Name | chemokine (C-X-C motif) ligand 11 |
| Background | Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This antimicrobial gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014] |
| Function | Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses. [UniProt] |
| Highlight | Related products: CXCL11 antibodies; CXCL11 ELISA Kits; Related news: circNDUFB2, a circular RNA (circRNA), activates anti-tumor immunity New ELISA data calculation tool: Simplify the ELISA analysis by GainData |
| Title | Download Link |
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| ARG82966 Human CXCL11 / I-TAC ELISA Kit User manual |
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